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Characteristics of Pediatric Allergic Rhinitis With Different Disease Severity.
Mediators Inflamm
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Department of Otolaryngology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.
Although numerous studies have focused on diagnostic biomarkers to help identify allergic rhinitis (AR), data on the characteristics of pediatric AR with different severity is limited. We aimed to compare the characteristics of pediatric AR with different severity. A total of 1054 children with AR were enrolled and classified into mild intermittent AR, mild persistent AR, moderate-to-severe intermittent AR, and moderate-to-severe persistent AR.
View Article and Find Full Text PDFRisk Factors for Post Laryngectomy Pharyngocutaneous Fistula and Impact of Pharyngeal Suture Type on Fistula Characteristics.
Iran J Otorhinolaryngol
January 2025
Otolaryngology Department, San Antonio Catholic University of Murcia. Murcia, Spain.
Introduction: Pharyngocutaneous fistula (PCF) is the most common complication following total laryngectomy (TL). The factors contributing to its occurrence are still a matter of debate. The impact of suture type has been relatively underexplored.
View Article and Find Full Text PDFSex estimation in a Chilean population by mandibular analysis in cone beam computed tomography images.
BMC Oral Health
January 2025
Applied Morphology Research Center (CIMA), Faculty of Dentistry, Universidad de La Frontera, Temuco, Chile.
Background: Sex estimation is the first stage in the identification of an individual in the forensic context, and can be carried out from bone structures like the mandible. The aim of this study was to estimate sex from metric analysis of the mandible in cone beam computed tomography images (CBCT) of adult Chilean individuals.
Methods: Six mandibular measurements were analysed, five linear and one angular, in CBCT of adult Chilean individuals of both sexes.
Jinbei oral liquid for idiopathic pulmonary fibrosis: a randomized placebo-controlled trial.
Sci Rep
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Department of Respiratory and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People's Republic of China.
The traditional Chinese medicine compound preparation known as Jinbei Oral Liquid (JBOL) consists of 12 herbs, including Astragalus membranaceus (Fisch.) Bge, Codonopsis pilosula (Franch.) Nannf, et al.
View Article and Find Full Text PDFPhase II Randomized Trial of BI 730357, a Novel Oral RORγt Inhibitor, for Moderate-to-Severe Plaque Psoriasis.
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Probity Medical Research, Inc., Waterloo, ON, Canada; Alliance Clinical Trials, Waterloo, ON, Canada; Division of Dermatology, University of Toronto School of Medicine, Toronto, ON, Canada.
Trial Design: This two-part, double-blinded trial assessed the truncated retinoic acid-related orphan receptor γ (RORγt) inhibitor BI 730357 in plaque psoriasis.
Methods: Part 1: patients were randomized 2:2:2:2:1 to BI 730357 25, 50, 100, 200 mg, or placebo once daily (qd; fasting conditions); non-responders switched to higher doses. Part 2: a separate patient set was randomized 4:4:1 to BI 730357 400 mg qd, 200 mg twice daily, or placebo (fed conditions).
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