Female androgenetic alopecia belongs to the family of scar-less, diffuse, telogenic, hormonally determined alopecias with hereditary disposition. In the androgenetic alopecia, progressive, androgen mediated miniaturization of genetically predestined hair follicles develops. Genetic factors play a role namely in females without the higher serum androgen level. Pathologically high level of serum androgens is usually accompanied with signs of virilization. Hair dropping starts in the fourth decade or earlier. It occurs in the postmenopausal period, after a pregnancy, after the onset or termination of peroral contraception, in women treated by aromatase inhibitors.
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J Cosmet Dermatol
January 2025
Dermatology and Venereology Department, Eskisehir Osmangazi University, Eskisehir, Turkey.
Background: Seborrheic dermatitis (SD) is a chronic, inflammatory disease characterized by unknown etiopathogenesis. It affects skin areas rich in sebaceous glands. There are strong data on the relationship between nutrition habits, body mass index (BMI), psychoemotional status, and sebaceous gland diseases such as acne, rosacea, and androgenetic alopecia.
View Article and Find Full Text PDFDermatol Reports
November 2024
Department of Dermatology, King Saud University Medical City, Riyadh.
Nowadays androgenetic alopecia (AGA) has become a common concern of affected subjects of both sexes. Finasteride is approved by the Food and Drug Administration for the treatment of male AGA. There is no clear evidence to support the use of dutasteride in male AGA.
View Article and Find Full Text PDFInt J Nanomedicine
December 2024
School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, Guangdong Province, People's Republic of China.
Introduction: Alopecia is a systemic disease with multiple contributing factors. Effective treatment is challenging when only hair growth mechanisms are targeted while ignoring the role of maintaining hair follicle microenvironment homeostasis, which is crucial for cell growth and angiogenesis. Oxidative stress and inflammation are major disruptors of this microenvironment, leading to inhibited cell proliferation and compromised hair follicle circulation.
View Article and Find Full Text PDFJ Invest Dermatol
December 2024
Department of Dermatology, China-Japan Friendship Hospital, Beijing, China. Electronic address:
With the widespread prevalence of COVID-19, researches have suggested a potential link between androgens and COVID-19 outcomes. However, the relationship between COVID-19 and androgenetic alopecia (AGA)-a condition strongly influenced by androgens-remains controversial in existing studies. Notably, there is a lack of large-scale clinical studies, particularly concerning data on the Chinese population following infection with the Omicron variant.
View Article and Find Full Text PDFIran J Pathol
July 2024
Department of Dermatology, Pathology and Stem Cells Research Center, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Background & Objective: FFA usually has a gradual subtle course and might be overlooked by physicians or misdiagnosed with other types of hair loss including androgenetic alopecia, traction alopecia, and other types of patterned alopecia. In this study, we described clinicopathological features of patients with FFA referring for skin biopsy.
Methods: This is a retrospective cross-sectional study on 26 patients with a diagnosis of FFA based on clinicopathological features.
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