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Article Synopsis
  • Laryngeal edema can cause serious airway obstruction, particularly in patients with inflammation of the epiglottis and vocal cords, making careful extubation important.
  • Traditional deep extubation is preferred for comfort and to reduce laryngeal edema risk, but cases of difficult mask ventilation (DMV) might require awake extubation.
  • In a case involving a child with obstructive sleep apnea who was at high risk for laryngeal edema, a retrograde lidocaine spray was used to numb the airway and facilitate a smoother awake extubation while minimizing coughing.
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Comfortably numb: Ecotoxicity of the non-steroidal anti-inflammatory drug ibuprofen on Phaeodactylum tricornutum.

Mar Environ Res

October 2020

MARE - Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016, Lisbon, Portugal; Departamento de Biologia Vegetal, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016, Lisboa, Portugal.

Emerging pollutants such as pharmaceuticals are continuously released to aquatic environments posing a rising threat to marine ecosystems. Yet, monitoring routines and ecotoxicity data on biota worldwide for these substances are lacking. Non-steroidal anti-inflammatory drugs are among the most prescribed and found pharmaceuticals in aquatic environments.

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Purpose: To explore personal experiences of loss of foot sensation following stroke in order to inform the focus of clinical assessments and development of a vibrotactile insole.

Methods: Qualitative design with an interpretive phenomenological approach to data collection and analysis. Eight community dwelling adults with stroke (>6 months) and sensory impairment in the feet participated.

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Objective: The efficacy of various pre-medication strategies for comfort management during microfocused ultrasound with visualization (MFU-V) treatment has not been studied. The present objective was to compare 2 topical analgesics (lidocaine 4% and benzocaine 20%) formulated with a novel transdermal delivery system with compounded lidocaine 23%/tetracaine 7% (23/7) to mitigate discomfort during MFU-V treatment.

Methods: This was a randomized, double-blinded, split-face study.

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Comfortably Numb: The Role of Momentary Dissociation in the Experience of Negative Affect Around Binge Eating.

J Nerv Ment Dis

May 2017

*Department of Clinical Research, Neuropsychiatric Research Institute; †Department of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, Fargo, ND; ‡Douglas Mental Health University Institute; and §Departments of Psychiatry and Psychology, McGill University, Montreal, Quebec, Canada.

Evidence suggests that both dissociation and negative affect (NA) may precipitate binge eating. The extent to which dissociation may impact the experience of NA around binge eating is unclear. Women with bulimia nervosa completed a 2-week ecological momentary assessment protocol of dissociation, NA, and binge eating.

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