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[Adult-onset of Still's disease with atypical articular and skin manifestations].
Tunis Med
December 2010
Service de Rhumatologie, CHU de Monastir, Université Monastir, Tunisia.
Background: Adult-onset Still's disease (ASD) is an uncommon clinical entity. It is a diagnosis of exclusion, characterized by a clinical triad of intermittent fever spikes, evanescent rash, and either arthralgia or arthritis. Destructive arthritis more commonly affects the hips, wrists, tarsal joints and cervical spine.
View Article and Find Full Text PDFAdult-onset Still's disease with vesiculopustules on the hands and feet.
J Korean Med Sci
December 2002
Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology characterized by an evanescent rash, intermittent spiking high fever, arthralgia, and a variety of systemic features. We describe a 46-yr-old woman with Still s disease who presented with a 2-month history of a symmetrical vesiculopustular eruptions only on both hands and feet. Skin biopsy specimens of both vesicle and pustule revealed fibrin thrombi deposition in the small dermal vessels with little inflammation, subepidermal bulla, and ischemic necrosis of the overlying epidermis, which were consistent with a vasculopathic reaction.
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