A short cut review was carried out to establish whether beta blockers should be used in the treatment of chest pain associated with cocaine use. 12 papers were found, of which two presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. The clinical bottom line is that Beta Blockers should not be used in the treatment of cocaine induced myocardial ischaemia.
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http://dx.doi.org/10.1136/emj.2006.036582 | DOI Listing |
Prev Sci
January 2025
School of Behavioral Health Sciences, The University of Texas Health Science Center at Houston, 7000 Fannin St, Houston, TX, 77030, USA.
Developing accurate and equitable screening protocols can lead to more targeted, efficient, and effective, teen dating violence (TDV) prevention programming. Current TDV screening protocols perform poorly and are rarely implemented, but recent research and policy emphasizes the importance of leveraging more trauma-focused screening measures for improved prevention outcomes. In response, the present study examined which adversities (i.
View Article and Find Full Text PDFEur J Dent
January 2025
Department of Orthodontic, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Objective: The mechanical stimulation known as orthodontic mechanical force (OMF) causes biological reactions in orthodontic tooth movement (OTM). Heat shock protein-70 (HSP-70) needs pro-inflammatory cytokines to trigger bone resorption in OTM; nevertheless, heat shock protein-10 (HSP-10), a "Alarmin" cytokine, should control these pro-inflammatory cytokines to get the best alveolar bone remodeling (ABR). L.
View Article and Find Full Text PDFSemin Cell Dev Biol
January 2025
Personalised Oncology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia; Department of Medical Biology, University of Melbourne, Melbourne, Australia. Electronic address:
The glioblastoma tumour microenvironment is characterised by immense heterogeneity, with malignant and non-malignant cells that interact in a complex ecosystem. Emerging evidence suggests that the tumour microenvironment is key in facilitating rapid proliferation, invasion, migration and cancer cell survival, crucial for treatment resistance. Spatial omics technologies have enabled the molecular characterisation of regions or individual cells within their spatial context, providing previously unattainable insights into the complex organisation of the glioblastoma tumour microenvironment.
View Article and Find Full Text PDFAppl Ergon
January 2025
Idaho National Laboratory, 1955 Fremont Avenue, Idaho Falls, ID, 83415, United States.
Human system interface design in industrial process control is guided by industry standards, human factors best practices, and domain-specific conventions, and often there is a conflict between one or more of the sources of design input for specific design elements. In the nuclear domain, one design element for which conflict arises is the use of color to represent equipment state. This study evaluates the tradeoffs associated with using color in a process control display versus using white and shades of gray.
View Article and Find Full Text PDFUrogynecology (Phila)
December 2024
From the Urogynecology and Reconstructive Pelvic Surgery, MedStar Washington Hospital Center/Georgetown University, Washington, DC.
Importance: Strong evidence demonstrates long-term cognitive decline associated with anticholinergics. While prevalent among older populations, medical management of overactive bladder (OAB) is dictated by insurance coverage rather than medical provider and patient preferences.
Objective: The aim of this study was to assess Medicare insurance plan coverage for select OAB medications and evaluate coverage of preferred medications to medications with a greater risk of cognitive dysfunction.
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