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Role of pre-diagnostic reproductive factors on long-term (10 years or greater) survival of epithelial ovarian cancer: The Extreme study.
Int J Gynecol Cancer
January 2025
Danish Cancer Institute, Virus, Lifestyle and Genes, Copenhagen, Denmark; University of Copenhagen, Department of Clinical Medicine, Copenhagen, Denmark; Rigshospitalet, Copenhagen University Hospital, Department of Gynecology, Copenhagen, Denmark. Electronic address:
Objective: Several reproductive factors are associated with ovarian cancer risk but the association with survival is less clear. The main aim was to examine the impact of pre-diagnostic reproductive factors on long-term ovarian cancer survival (≥10 years).
Methods: We included all women with epithelial ovarian cancer in Denmark, 1990-2014.
Physicians' knowledge, attitudes, and beliefs regarding practices of male and female surgical sterilization procedures in Lebanon.
Contracept Reprod Med
January 2025
Department of Surgery, Division of Urology, American University of Beirut Medical Center, Riad El-Solh, Beirut, 1107 2020, Lebanon.
Objective: Surgical sterilization, including vasectomy in males and tubal ligation in females, is a highly effective but underutilized contraception method. Adoption rates vary globally mostly due to misconceptions by both the general public and practicing physicians. Our survey aims to explore physicians' knowledge, attitudes and beliefs about surgical sterilization techniques in Lebanon.
View Article and Find Full Text PDFHuman fallopian tube organoids provide a favourable environment for sperm motility.
Hum Reprod
January 2025
IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III-Paul Sabatier (UPS), Toulouse, France.
Study Question: Does a human fallopian tube (HFT) organoid model offer a favourable apical environment for human sperm survival and motility?
Summary Answer: After differentiation, the apical compartment of a new HFT organoid model provides a favourable environment for sperm motility, which is better than commercial media.
What Is Known Already: HFTs are the site of major events that are crucial for achieving an ongoing pregnancy, such as gamete survival and competence, fertilization steps, and preimplantation embryo development. In order to better understand the tubal physiology and tubal factors involved in these reproductive functions, and to improve still suboptimal in vitro conditions for gamete preparation and embryo culture during IVF, we sought to develop an HFT organoid model from isolated adult stem cells to allow spermatozoa co-culture in the apical compartment.
Tubal Sterilization And Vasectomy Increased Among US Young Adults After The Supreme Court Decision In 2022.
Health Aff (Millwood)
January 2025
Julie Maslowsky, University of Michigan, Ann Arbor, Michigan.
Young adults' access to contraception is shifting after the June 2022 United States Supreme Court decision. This concurrent mixed-methods study measured young adults' use of and perceptions about tubal sterilization and vasectomy after the leaked opinion in May 2022. Using national-level medical claims data from IQVIA, we conducted difference-in-differences analyses of tubal sterilizations and vasectomies by age and state policy; using open-text survey responses from national MyVoice surveys in 2022 and 2023, we thematically analyzed young adults' perspectives.
View Article and Find Full Text PDFProvider views on vasectomy: cultural, gender, and political elements of Men's decisions to seek publicly funded services.
Front Reprod Health
December 2024
Collaborative Center to Advance Health Services, University of Missouri Kansas City, Kanas City, MO, United States.
Article Synopsis
- There is an increasing interest in vasectomies following the Supreme Court's Dobbs decision, highlighting their safety and cost-effectiveness compared to tubal sterilization.
- Health care providers from Title X-funded clinics were interviewed to understand the cultural, gender, and political influences on men's decisions to seek vasectomies.
- Key barriers identified included income challenges, language barriers, medical distrust, and traditional gender roles, but many men expressed a strong desire to take responsibility for contraception and contribute to reproductive health equity.
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