The nonlinearity characteristics of a commercially available thin-film photoconductive PbS detector were experimentally investigated in the infrared using the National Physical Laboratory detector linearity characterization facility. The deviation from linearity of this detector was shown to be significant even for relatively low values of radiant power incident on the active area of the detector. For example, the linearity factor was approximately 0.8 when 0.6 microW of radiant power at a wavelength of 2.2 microm was illuminating a spot of 1 mm in diameter on the active area of the PbS detector. These figures demonstrate the poor linearity characteristics of this detector and provide a warning to other users of PbS detection systems. The deviation from linearity was shown to be a function of the size of the spot being illuminated on the detector active area, as well as the wavelength of the incident radiation. The deviation from linearity was shown to be a function of irradiance illuminating the detector for irradiance values lower than 1 microW mm(-2).
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1364/ao.45.002381 | DOI Listing |
Front Oncol
November 2024
Department of Radiation Oncology, University of Washington School of Medicine, Seattle, WA, United States.
Background: This manuscript describes modifications to a pencil beam scanning (PBS) proton gantry that enables ultra-high dose rates (UHDR) irradiation, including treatment planning and validation.
Methods: Beamline modifications consisted of opening the energy slits and setting the degrader to pass-through mode to maximize the dose rate. A range shifter was inserted upstream from the isocenter to enlarge the spot size and make it rotationally symmetric.
Biomed Phys Eng Express
December 2024
Department of Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Iron Deficiency Anemia (IDA) is the nutritional disorder that occurs when the body does not contain enough iron, an essential component of hemoglobin (Hb). The World Health Organization (WHO) estimated that IDA is the main cause of anemia in 1.62 billion cases worldwide [1].
View Article and Find Full Text PDFMed Phys
November 2024
HollandPTC, Delft, The Netherlands.
Background: Pre-clinical studies demonstrate that delivering a high dose at a high dose rate result in less toxicity while maintaining tumor control, known as the FLASH effect. In proton therapy, clinical trials have started using 250 MeV transmission beams and more trials are foreseen. A novel aspect of FLASH treatments, compared to conventional radiotherapy, is the importance of dose rate next to dose and geometry.
View Article and Find Full Text PDFMicrosyst Nanoeng
November 2024
Chemical and Biological Engineering, University of British Columbia, Vancouver, Canada.
Lactate measurements provide an opportunity to conveniently evaluate bodily functions and sports performance. A molecularly imprinted fluorescence biochip provides an innovative way to achieve lactate measurement and overcomes the limitations of enzyme-based sensors. To realize this goal, ZnO quantum dots (QDs), a biocompatible sensing material, were combined with selective receptors comprised of molecularly imprinted polymers (MIPs).
View Article and Find Full Text PDFBioorg Chem
December 2024
University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03 Hradec Kralove, Czech Republic; University Hospital in Hradec Kralove, Biomedical Research Centre, Sokolska 581, 500 05 Hradec Kralove, Czech Republic. Electronic address:
Mono-quaternary pyridinium oximes derived from K-oximes K027, K048 and K203 were designed, synthesized and evaluated for the reactivation of organophosphate-inhibited cholinesterases. The incorporation of the halogen atoms to the structure decreased the pK value of the oxime group resulting in an increased formation of oximate necessary for reactivation. The stability and pK values were found to be similar to analogous bis-quaternary compounds.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!