Several alternatives to psychostimulants have been developed and expanded the variability of the treatment of ADHD. Clonidine is a good option for managing core behavioral symptoms, especially hyperactivity and impulsivity. Bupropion and venlafaxine seem potentially promising. Significant new options include norepinephrine reuptake inhibitors, such as atomoxetine, and possibly selective dopamine agonists. Central anticholinesterases, such as donepezil, may improve core ADHD symptoms.
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Naunyn Schmiedebergs Arch Pharmacol
January 2025
Faculty of Pharmacy, Integral University, Lucknow, 226026, India.
Alopecia, a common dermatological condition, poses significant psychological and social challenges. Despite the availability of various treatments, their efficacy is often limited by poor bioavailability and delivery challenges. Nanostructured lipid carriers have emerged as promising advanced drug delivery systems for alopecia treatment due to their ability to encapsulate both hydrophilic and lipophilic compounds, enhancing their stability, solubility, and controlled release.
View Article and Find Full Text PDFLangenbecks Arch Surg
January 2025
Department of Trauma Surgery, University Hospital Zurich, Rämistrasse 100, CH - 8091, Zurich, Switzerland.
Introduction: Blunt traumatic aortic injury (TAI) is a critical condition and a leading cause of mortality in trauma patients, often resulting from high-speed accidents. Thoracic endovascular aortic repair (TEVAR) has developed into the preferred therapeutic approach due to its minimally invasive nature and promising outcomes. This study evaluates the safety and efficacy of TEVAR for managing TAI over a 10-year period at a Level-1 trauma center.
View Article and Find Full Text PDFRisk Anal
January 2025
School of Business, Maynooth University, Maynooth, Ireland.
Chemicals in general often evoke negative emotions (e.g., worry or fear) in consumers.
View Article and Find Full Text PDFJ Commun Healthc
January 2025
Venditti Consulting, LLC, Westport, CT, United States.
By addressing communication gaps, the integration of AI tools in healthcare has a greater ability to improve decision-making and to empower patients with more control over their health. Current systems for navigating healthcare - such as finding providers or understanding costs - are fragmented and cumbersome, often leaving patients frustrated and uninformed. An AI Healthcare Assistant App, leveraging advances in health IT interoperability, price transparency, and user-centred design, could simplify these processes.
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