Assessing the reproducibility of an analytical method.

J Chromatogr Sci

Merck Research Laboratories, P.O. Box 4, WP37C-305, West Point, PA 19486, USA.

Published: March 2006

The reproducibility of a validated analytical method may require reassessment because of various reasons, such as the transfer between laboratories or companies, changes in the instruments or software platforms (or both), or changes in critical reagents, among others. This paper is a demonstration of an assay bridging study in evaluating reproducibility. The approach is simple but very informative and offers many advantages over existing approaches.

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http://dx.doi.org/10.1093/chromsci/44.3.119DOI Listing

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