It was established in acute experiments on dogs and rabbits that craniocerebral trauma does not lead to the development of torpid shock. In combination of craniocerebral trauma with severe mechanical injury to the thigh or acute massive extracranial blood loss a typical torpid shock develops with death of the animals in the immediate hours. Infusion therapy relieves shock but fails to prevent the development of brain edema. Intravenous injections of procaine hydrochloride have a positive effect in craniocerebral trauma and shock. It is concluded that craniocerebral trauma does not disturb the mechanisms of shock formation and the process takes a course independently of the process of brain edema development.

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