The effects of azadirachtin A added to the standard diet on the development, mortality, and metamorphosis of Lutzomyia longipalpis Lutz & Neiva, 1912 were studied. Concentrations of 0.1, 1.0, and 10.0 microg of azadirachtin/mg of diet significantly increased larval mortality in comparison with nontreated insects. Concentrations 0.1 and 1.0 microg blocked the molt of larvae, which remained as third instars until the end of the experiment. The 10 microg/mg concentration resulted in greater molt inhibition. In this group, all insects stopped their development as second instars. Simultaneous addition of ecdysone (1 microg/mg) to the standard diet containing azadirachtin counteracted the effects of azadirachtin on mortality and inhibition of ecdysis. These results indicate that azadirachtin is a potent growth inhibitor of L. longipalpis.
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http://dx.doi.org/10.1603/0022-2585(2006)043[0262:eoaotd]2.0.co;2 | DOI Listing |
J Econ Entomol
January 2025
MARA-CABI Joint Laboratory for Bio-safety, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.
Chemical control is currently the main strategy for managing brown marmorated stink bug, Halyomorpha halys (Stål). However, chemical pesticides can harm nontarget species, including natural enemies of H. halys.
View Article and Find Full Text PDFParasit Vectors
December 2024
Department of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic.
Background: Leishmaniasis is a group of neglected vector-borne diseases transmitted by phlebotomine sand flies. Leishmania parasites must overcome various defenses in the sand fly midgut, including the insects's immune response. Insect immunity is regulated by the ecdysone hormone, which binds to its nuclear receptor (EcR) and activates the transcription of genes involved in insect immunity.
View Article and Find Full Text PDFPestic Biochem Physiol
December 2024
State Key Laboratory of Green Pesticide, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, Shaoguan University, Guangzhou 510642, China. Electronic address:
The high toxicity of thiamethoxam (Thi) to foragers has threatened the development of bee populations and the use of neonicotinoid pesticides. In this study, we explored the mechanism of selective feeding on azadirachtin (Aza) by foragers to reduce the feeding of Aza-Thi and improve foragers' safety. The results showed that foragers under selective feeding significantly reduced the Aza sucrose solution intake.
View Article and Find Full Text PDFJ Biomol Struct Dyn
December 2024
Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
In traditional medicine, potential anti-inflammatory and pain-relieving activity of and has been emphasized. In this study, we explored binding affinity of 36 bioactive compounds from these plants to cyclooxygenase-2 (COX-2) receptor using docking method. Six compounds namely, beta carotene, lycopene, lutein, momordicoside, rutin and azadirachtin showed excellent binding affinities (-10.
View Article and Find Full Text PDFToxicon
January 2025
Entomology Research Institute, Loyola Campus, Chennai, 600034, India.
Mosquitoes, as hematophagous ectoparasites, are significant pests and vectors of numerous pathogens, causing diseases such as dengue, lymphatic filariasis, malaria, chikungunya, and Japanese encephalitis in India. This study investigates the potential of natural insecticides derived from plants to combat mosquito populations, focusing on botanical extract from the leave of Sphaeranthus indicus. Specifically, the hexane extract of S.
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