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Background: Rhabdomyolysis is frequently associated with acute kidney injury (AKI). Due to the nephrotoxic properties of myoglobin, its rapid removal is relevant. If kidney replacement therapy (KRT) is necessary for AKI, a procedure with effective myoglobin elimination should be preferred.

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Idiopathic inflammatory myopathy and C3 glomerulopathy: a rare association.

J Nephrol

December 2024

Unit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, A.O.U. "G.Martino", University of Messina, 98125, Messina, Italy.

Idiopathic inflammatory myopathies represent a spectrum of autoimmune disorders primarily characterized by muscle inflammation. While renal involvement in idiopathic inflammatory myopathies has historically been considered rare, recent findings indicate a prevalence of approximately 21-23%. Renal manifestations in idiopathic inflammatory myopathies are generally secondary to acute renal injury from rhabdomyolysis or, more rarely, occur through autoimmune mechanisms leading to glomerulonephritis.

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Purpose: The risk of exercise-induced rhabdomyolysis, followed by abrupt creatine kinase (CK) augmentation, associated with carnitine palmitoyl transferase II (CPTII) deficiency causes patients to abstain from physical training. However, the exercise adjustment to the disease-induced metabolic impairment, accompanied by a tailored nutritional and supplementation strategy, could make sporting activity feasible, even at a competitive level. Here, we report the case of an 18-year-old male basketball player at a competitive level diagnosed for CPTII deficiency after a rhabdomyolytic event.

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Acute renal failure requiring renal replacement therapy secondary to rhabdomyolysis due to rosuvastatin.

Ann Med Surg (Lond)

November 2024

Maharajgunj Medical Campus, Institute of Medicine, Department of Internal Medicine, Tribhuvan University, Kathmandu, Nepal.

Introduction And Importance: Statins are the group of medicines that lower the level of low-density lipoprotein cholesterol. One of the life-threatening complications is rhabdomyolysis as the use of these drugs.

Case Presentation: Here, we report a case of a 69-year-old female who was diagnosed with non-ST elevation myocardial infarction one month and was on regular medication before presentation with generalized weakness and decreased urine output.

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