AI Article Synopsis
- - An adult patient developed acute anterior poliomyelitis (AAP) 28 days after his son received the oral poliovirus vaccine (OPV), revealing a possible connection between the two.
- - Neurological tests indicated that the patient's left lower limb weakness was due to a lower motor neuron disorder, confirmed by MRI showing a lesion in the left anterior horn.
- - The patient's stool tested positive for poliovirus type 3, linked to the vaccine strain, raising concerns about the safety and implications of using OPV in countries where polio is no longer prevalent.
Article Abstract
We encountered an adult patient with acute anterior poliomyelitis (AAP), whose monoparesis developed 28 days after his son's immunization with oral poliovirus vaccine (OPV). Neurological and electrophysiological examinations suggested that his muscular wasting of the left lower limb was due to a lower motor neuron disorder, and magnetic resonance imaging revealed the responsible lesion in the left anterior horn at the thoracolumbar junction. His stool was found to include poliovirus type 3, mainly originating from Sabin 3 by neutrization antibody and PCR-restriction fragment length polymorphism method. This indicated that the AAP resulted from contact with his son. This patient raises the question about OPV in polio-free countries.
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| http://dx.doi.org/10.2169/internalmedicine.45.1622 | DOI Listing |
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