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dressing based on a D-π-A structured aggregation-induced emission photosensitizer for healing infected wounds.
J Mater Chem B
December 2024
School of Biomedical Engineering and Digital Health, School of Science, Harbin Institute of Technology (Shenzhen), Shenzhen, Guangdong, 518055, China.
Photodynamic antimicrobial therapy (aPDT) can effectively kill bacteria without promoting drug resistance. However, the phototoxicity of photosensitizers in aPDT against normal cells hinders their practical applications. In this work, we report the utilization of an aggregation-induced emission (AIE)-active photosensitizer, DTTPB, to develop antibacterial dressing for effective eradication of both Gram-positive and Gram-negative bacteria.
View Article and Find Full Text PDFPerioperative acute kidney injury - cloaked and hidden - know your enemy.
Pol Merkur Lekarski
December 2024
1ST DEPARTMENT OF ANESTHESIOLOGY AND INTENSIVE CARE, INFANT JESUS CLINICAL HOSPITAL UCC MUW, WARSAW, POLAND.
Surgery and anaesthesia come with adverse effects. As obvious as it is, not all of them are considered frequently enough. It may seem reasonable because some of them kill instantly.
View Article and Find Full Text PDFAptamer modified CeCo MOF hybrid catalysts with multiple enzymatic activities for enhanced catalytic therapy of infected wounds.
Int J Biol Macromol
January 2025
Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Nursing, Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou 510006, Guangdong, China. Electronic address:
Designing and inventing synergistic emerging antimicrobial strategies is critical for mitigating potential resistance to conventional antibiotics. This task is challenging because these antimicrobial agents should need to eliminate bacteria, slow oxidative stress in wounds, and be safe and nontoxic. Here, we report a highly safe antimicrobial nanocatalyst for bacterial scavenging through aptamer-synergistic multienzyme activity.
View Article and Find Full Text PDFViews on medical assistance in dying and related arguments: a survey of doctors and nurses at a university hospital.
BMC Med Ethics
November 2024
University of Iceland, Faculty of Medicine, Reykjavik, Iceland.
Background: In 2021, a survey was conducted among doctors and nurses at Landspítali Iceland University Hospital (LIUH) regarding their views on medical assistance in dying (MAID) and the underlying arguments, the inclusion criteria and modality of implementation. Surveys on identically defined study groups in 1995 and 2010 were used for comparison.
Methods: The survey was sent to 357 doctors and 516 nurses working at LIUH.
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