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J Tissue Eng
June 2024
Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Tissue engineering approaches hold great promise in the field of regenerative medicine, especially in the context of pediatric applications, where ideal grafts need to restore the function of the targeted tissue and consider growth. In the present study, we aimed to develop a protocol to engineer autologous phalangeal grafts of relevant size for children suffering from symbrachydactyly. This condition results in hands with short fingers and missing bones.
View Article and Find Full Text PDFGlob Pediatr Health
December 2023
Pediatric Radiology Department, Pediatric Teaching Hospital, Mohammed V University, Rabat, Morocco.
Poland syndrome is indeed a rare congenital malformation that can present with various degrees of thoracic and homolateral upper limb anomalies. The classic features of Poland syndrome include agenesis or hypoplasia of the sternocostal head of the pectoralis major muscle, hypoplasia of the nipple, absence of subcutaneous fat, multiple rib abnormalities, and sometimes Sprengel deformity (elevation of the scapula). Additionally, ipsilateral symbrachydactyly (combination of "short fingers" with cutaneous syndactyly [fused fingers]) may also be observed.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
November 2023
From the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Tex.
Background: Poland syndrome is classically described as symbrachydactyly, with hypoplasia of the pectoralis major and other upper thoracic musculoskeletal structures. It is thought to be caused by intrauterine interruption in subclavian arterial flow and often includes breast hypoplasia. Affected vasculature can pose a challenge for reconstruction with free flaps because inflow may not be reliable in this patient population.
View Article and Find Full Text PDFCureus
July 2023
Pediatrics, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, Florida, USA.
Symbrachydactyly is a complex and rare congenital hand deformity characterized by missing or underdeveloped fingers and rudimentary digit nubbins. This case report focuses on a newborn female with type 3A symbrachydactyly, highlighting the unique clinical presentation, diagnostic assessment, and initial management approach. The rarity of this condition underscores the need for sharing cases to enhance understanding and treatment strategies.
View Article and Find Full Text PDFAnn Med Surg (Lond)
March 2023
Department of Surgery, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal.
Unlabelled: Poland syndrome is a rare congenital syndrome that mostly includes the absence of unilateral pectoralis major muscle and digit anomalies like symbrachydactyly. It can also present with other varied manifestations like the absence of ribs, bilateral absence of pectoralis major muscle, urogenital anomalies, dextrocardia, etc.
Case Presentation: We herein present a case of a 6-year-old boy with Poland syndrome as an incidental finding, the second one reported from Nepal, 11 years after the first report.
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