Research on the treatment of drooling applies measures such as salivary flow rate, qualitative observations of drooling severity in standardized situations, and anecdotal or one-dimensional parental and teacher reports. To assess drooling severity in a range of everyday conditions, and its impact on the daily life of children and their families, two parent questionnaires were constructed. Results of baseline measurements of 43 children with cerebral palsy showed that the questionnaires measured the variation in drooling severity across daily life conditions, and enabled evaluation of the impact of drooling on the ability to eat, drink and speak, on daily care, economic consequences, and social interactions. The section on the impact of drooling on self-esteem appeared not to be fully applicable for non-speaking children with a low developmental status. The questionnaires offer a qualitative method to evaluate parental perceptions of the impact of drooling and evaluate the effectiveness of interventions to reduce drooling.
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http://dx.doi.org/10.1097/01.mrr.0000194395.64396.f1 | DOI Listing |
Curr Opin Oncol
January 2025
Gustave Roussy Departement Interdisciplinaire de Soins de Support aux Patients en Onco-hematologie, Villejuif, France.
Purpose Of Review: Immune checkpoint inhibitors (ICI) have become an integral part of oncology treatment. ICI currently has approval for more than thirty tumor types with proven efficacy. However, ICI can expose patients to inflammatory side effects, such as immuno-related adverse events (irAE).
View Article and Find Full Text PDFJ Dev Orig Health Dis
January 2025
Department of Nutrition, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
To clarify the effects of kefir in critical periods of development in adult diseases, we study the effects of kefir intake during early life on gut microbiota and prevention of colorectal carcinogenesis in adulthood. Lactating Wistar rats were divided into three groups: control (C), kefir lactation (KL), and kefir puberty (KP) groups. The C and KP groups received 1 mL of water/day; KL dams received kefir milk daily (10 CFU/mL) during lactation.
View Article and Find Full Text PDFEndocrinol Diabetes Metab Case Rep
January 2025
Summary: Vitamin D is commonly recommended for daily intake as dietary sources are often insufficient. However, prolonged high-dose use can lead to serious complications. We present a rare case of a 2-month-old infant who developed severe hypercalcemia and hypertriglyceridemia due to an accidental overdose of 25-OH vitamin D, leading to hypertriglyceridemia and pancreatitis.
View Article and Find Full Text PDFGlobal Spine J
January 2025
NYU Langone Health, New York, NY, USA.
Study Design: cross-sectional survey.
Objectives: To evaluate AO Spine members' practices and comfort in managing metastatic and primary spine tumors, explore the use of decision-support and patient assessment tools, and identify knowledge gaps and future needs in spine oncology.
Methods: An online survey was distributed to AO Spine members to query comfort levels with key decisions in spinal oncology management, utilization of decision frameworks and spine oncology-specific instruments, and educational material preferences.
Pak J Med Sci
January 2025
Jun Zang Neurological Rehabilitation Center, Beijing Rehabilitation Hospital of Capital Medical University, Beijing 100000, Beijing, China.
Objective: To evaluate the clinical efficacy of bladder function training combined with pelvic floor biofeedback electrical stimulation in the treatment of neurogenic bladder and its impact on urodynamics.
Methods: This was a clinical comparative study. A total of 120 patients with neurogenic bladder after spinal cord injury admitted to Beijing Rehabilitation Hospital of Capital Medical University and Beijing Shijingshan Hospital from January 2023 to December 2023 were randomly divided into two groups (n= 60/group).
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