A mixed-valent ruthenium-oxo oxalato cluster Na7[Ru4(mu3-O)4(C2O4)6] with potent anti-HIV activities.

Ella Lai-Ming Wong Raymond Wai-Yin Sun Nancy P-Y Chung Chen-Lung Steve Lin Nianyong Zhu Chi-Ming Che

J Am Chem Soc

Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong.

Published: April 2006

A structurally characterized mixed-valent tetranuclear ruthenium-oxo oxalato cluster exhibits anti-viral activities toward R5- and X4-tropic HIV-1, and possesses cytoprotective activity toward HIV-1 infected cells.

Download full-text PDF	Source
http://dx.doi.org/10.1021/ja057883k	DOI Listing

Publication Analysis

Top Keywords

ruthenium-oxo oxalato

oxalato cluster

mixed-valent ruthenium-oxo

cluster na7[ru4mu3-o4c2o46]

na7[ru4mu3-o4c2o46] potent

potent anti-hiv

anti-hiv activities

activities structurally

structurally characterized

characterized mixed-valent

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!