[Pharmacological treatment of COPD and future of anti-inflammatory therapy].

Med Klin (Munich)

Zentrum für Pneumologie und Thoraxchirurgie, Pneumologisches Forschungsinstitut am Krankenhaus Grosshansdorf, Grosshansdorf.

Published: April 2006

Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation that is not fully reversible. It is caused by chronic inflammation of the airways and the lung parenchyma. Symptomatic treatment is based on bronchodilatation, which leads to a reduction of hyperinflation and relief of dyspnea. Smoking cessation is the only known causative treatment option. Inhaled corticosteroids (ICS) reduce exacerbations and, potentially, mortality. Future therapies should ameliorate chronic inflammation and thus stop the annual decline of lung function. In face of increasing mortality and morbidity more research is needed.

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Source
http://dx.doi.org/10.1007/s00063-006-1036-6DOI Listing

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