AI Article Synopsis
- The study aimed to evaluate the impact of postponing a specific fetal surgery (tracheal occlusion) on the survival of fetuses with a serious condition known as congenital diaphragmatic hernia.
- Eight fetuses underwent the procedure between 29 and 32 weeks of pregnancy, with a focus on reducing risks associated with premature delivery and ensuring comprehensive postnatal care.
- Results showed that 6 out of 8 fetuses survived after the surgery, suggesting that delaying the procedure can support lung development and improve survival chances for affected fetuses.
Article Abstract
Objective: In order to assess the effect of deliberately delayed percutaneous fetoscopic tracheal occlusion on survival of fetuses with life-threatening congenital diaphragmatic hernia.
Methods: Eight fetuses with life-threatening congenital diaphragmatic hernia underwent fetoscopic tracheal balloon occlusion between 29 + 0 and 32 + 4 weeks of gestation. Delayed occlusion was chosen in order to minimize potentially negative pulmonary effects from premature delivery as a result of fetal surgery. In addition, we wanted to become able to provide all available postnatal intensive care treatment means in these patients.
Results: Six of the 8 fetuses survived to discharge from hospital.
Conclusion: Delayed fetoscopic tracheal balloon occlusion may be rewarded with lung growth sufficient to allow survival of fetuses with life-threatening congenital diaphragmatic hernia.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000091363 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Echocardiographic Changes in Infants with Severe Congenital Diaphragmatic Hernia After Fetoscopic Endoluminal Tracheal Occlusion (FETO).
Pediatr Cardiol
December 2024
Division of Pediatric General, Thoracic, and Fetal Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Fetoscopic endoluminal tracheal occlusion (FETO) induces lung growth and may improve survival in congenital diaphragmatic hernia (CDH) but the effect on post-natal right (RV) and left (LV) ventricular size and cardiac function is unknown. Quantitative measures of heart size and function including tricuspid annular plane systolic excursion Z-score (TAPSEZ), RV fractional area change (RVFAC), RV global longitudinal and free wall strain (RVGLS, RVFWS), RV/LV ratio, LV eccentricity index (LVEI), and LV M-mode diastolic and systolic Z-scores (LVIDDZ, LVIDSZ) were compared between FETO and control patients on first post-natal echocardiogram, prior to and post CDH repair, and on last available echocardiogram using non-parametric Wilcoxon rank-sum test in a single-center, retrospective cohort study. Linear regression models evaluated change over time, adjusting for clustering and interaction of echocardiogram parameters with time.
View Article and Find Full Text PDFFeasibility, safety, and outcome of fetoscopic endoluminal tracheal occlusion for severe congenital diaphragmatic hernia at a low case-load center: one center's experience.
Ann Saudi Med
December 2024
From the Department of Obstetrics & Gynecology, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Background: Antenatal fetoscopic endoluminal tracheal occlusion (FETO) has been introduced as an effective intervention to improve the outcome of severe congenital diaphragmatic hernia (CDH).
Objective: We report our early experience with FETO.
Design: A retrospective chart review of case series.
Neonatal Airway Management and Outcomes Following Fetoscopic Endoluminal Tracheal Occlusion (FETO): A Single-Center Descriptive Analysis.
J Surg Res
December 2024
Division of Pediatric Surgery, Department of Surgery, Texas Children's Hospital and Baylor, College of Medicine, Houston, Texas; Texas Children's Fetal Center, Baylor College of Medicine, Houston, Texas. Electronic address:
Article Synopsis
- Congenital diaphragmatic hernia is a serious condition that can lead to issues like underdeveloped lungs and high blood pressure, but a procedure called fetoscopic endoluminal tracheal occlusion (FETO) has shown to improve patient survival despite some complications like tracheomegaly (enlarged trachea).
- A study analyzed 34 patients who underwent FETO, finding that tracheomegaly was present in 24 of them, with most needing intubation right after birth, some requiring a transition to cuffed endotracheal tubes (ETTs) due to concerns like air leaks.
- The findings suggest that larger or cuffed ETTs may be more beneficial for
Percutaneous Puncture of a Fetoscopic Endoluminal Tracheal Occlusion Balloon.
J Vasc Interv Radiol
November 2024
Division of Pediatric Surgery, Department of Surgery, University of Wisconsin, Madison, Wisconsin.
Anesthetic management for fetal surgery: Lessons from a single-center experience (2019-2023).
Int J Obstet Anesth
October 2024
Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Fetal Medicine Center, Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikvah, Israel.
Fetal surgery presents distinctive anesthetic challenges due to the need to balance maternal and fetal safety. This retrospective study evaluates the anesthetic management strategies used at a single center for various fetal interventions, including fetoscopic laser photocoagulation, fetal endoluminal tracheal occlusion, bipolar cord coagulation, and fetoscopic spina bifida repair. We reviewed 195 fetal procedures performed between 2019 and 2023 at Rabin Medical Center.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!