[Papillary cystadenocarcinoma in a Müllerian duct cyst: report of a case with literature review].

Zhonghua Nan Ke Xue

Department of Urology, the First Affiliated Hospital, Medicine School, Xi'an Jiaotong University, Shaanxi, China.

Published: March 2006

AI Article Synopsis

  • The study focuses on the diagnosis and treatment of Müllerian duct cysts and their potential link to malignancy, illustrated through a case of papillary cystadenocarcinoma in a 44-year-old male.
  • The patient experienced symptoms like hemospermia, hematuria, and infertility for 15 years, leading to various imaging and biopsy tests for diagnosis.
  • Surgical exploration confirmed the malignancy's origin from the Müllerian duct system, and the findings suggest that lumpectomy is a successful treatment option for these rare cases.

Article Abstract

Objective: To study the diagnosis and treatment of Müllerian duct cysts and their involvement with malignancy.

Methods: A 44-year-old male patient with papillary cystadenocarcinoma involving a Müllerian duct cyst was presented. The presentation treatment, and pathological and radiological appearances were retrospectively analysed and discussed with literature review. The main manifestation was intermittent episode of hemospermia accompanying terminal hematuria and infertility for 15 years. Final diagnosis was determined by the findings of transrectal ultrasound scan, CT scan, MRI imaging, cystoscopic examination and biopsy.

Results: Exploratory laparotomy was performed through a suprapubic retrovesical approach. The finding that a duct-like wedge of tumor tissue passed through the prostate near cyst neck to the posterior urethra without affecting the adjacent prostatic tissue during tylectomy confirmed that it arises from Müllerian duct system. Pathohistologic examination disclosed a papillary cystadenocarcinoma and it infiltrated the wall of the cyst. Both seminal vesicles and ejaculatory duct had no carcinoma invasion.

Conclusion: Müllerian duct cyst involving with malignancy is exceedingly rare, the diagnosis is based on the findings of transrectal ultrasound scan, CT scan, MRI imaging, cystoscopic examination. The final diagnosis depends on the pathohistologic examination. Lumpectomy is effective and have a good outcome.

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