AI Article Synopsis
- - The study involves five hemodialysis patients who had anemia and low white blood cell counts, which improved after addressing their copper deficiency.
- - After correcting the deficiency, the patients needed lower doses of erythropoietin to maintain their target hematocrit levels, with three of them completely stopping rHuEPO treatment.
- - The findings suggest that copper deficiency plays a significant role in causing anemia that doesn't respond to erythropoietin in patients undergoing hemodialysis.
Article Abstract
We have encountered five hemodialysis patients who had received enteral nutrition and recovered from erythropoietin-resistant anemia with neutropenia after the correction of copper deficiency. We reduced the required doses of recombinant human erythropoietin (rHuEPO) to maintain the target hematocrit levels and three patients were finally weaned from the rHuEPO therapy. Thus, copper deficiency is involved in erythropoietin-resistant anemia in hemodialysis patients.
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| http://dx.doi.org/10.2169/internalmedicine.45.1541 | DOI Listing |
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