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| http://dx.doi.org/10.1073/pnas.59.2.313 | DOI Listing |
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The data available from other laboratories as well as our own on the frequency of cells recognizing major histocompatibility antigens or conventional protein and hapten antigens is critically evaluated. The frequency of specific binding for a large number of antigens is sufficiently high to support the idea that at least part of the antigen-binding cell population must have multiple specificities. Our results suggest that these multiple specific cells result from single cells synthesizing and displaying as many as 50-100 species of receptor, each at a frequency of 10(4) per cell.
View Article and Find Full Text PDFNumerology of the constants of nature.
Proc Natl Acad Sci U S A
February 1968
DEPARTMENT OF PHYSICS AND ASTROPHYSICS, UNIVERSITY OF COLORADO, BOULDER.
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