Cross-language research using synthetic voice-onset-time series over the past 40 years suggests that the Spanish lead contrast is acoustically less salient than the English lag contrast. This study examined monkey identification of a labial consonant-vowel voice-onset-time (CV VOT) series (-60 to +70 ms) in order to obtain a linguistically unbiased estimate of lead versus lag salience. Comparisons were made with both English and Spanish adult human listeners. In a classic two-choice identification test, monkey and Spanish functions were quite variable and showed evidence of sensitivity to three types of voicing cues (lead versus simultaneous versus lag). In contrast, English functions were highly categorical and showed sensitivity to only two types of cues (combined lead/simultaneous versus lag). Next, listeners were explicitly trained via feedback to differentiate stimuli crossing lead and lag boundaries. Here, monkey and Spanish performance was initially more symmetrical than English performance, with the latter showing reduced sensitivity to the lead boundary, but group differences disappeared after extended training. These results provide evidence for perceptual loss in English listeners for aspects of Spanish voicing lead perception.
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http://dx.doi.org/10.1121/1.2162440 | DOI Listing |
Clin Epigenetics
January 2025
Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Background: Night shift work during pregnancy has been associated with differential DNA methylation in placental tissue, but no studies have explored this association in cord blood. We aimed to examine associations of maternal night shift work with cord blood DNA methylation.
Methods: A total of 4487 mother-newborn pairs from 7 studies were included.
BMC Pharmacol Toxicol
January 2025
Department of Community Medicine, Islamic International Medical College (IIMC), Riphah International University, Rawalpindi, Pakistan.
Objective: To determine the relative effectiveness of combination therapy of antidepressants with low-dose methylfolate versus antidepressant monotherapy in patients with depressive disorder.
Methods: In an open-label clinical trial, forty-four patients with depressive disorder (6A70, 6A71, and 6A72 according to ICD-11) received an evidence-based antidepressant therapy (either escitalopram 10-20 mg, sertraline 50-100 mg, fluoxetine 20-40 mg, duloxetine 30-60 mg, mirtazapine 15-30 mg, venlafaxine 75-150 mg, trazodone 50-100 mg, amitriptyline 25-75 mg, or clomipramine 25-75 mg orally daily for 4 weeks). The experimental group, Group B was additionally given a dose of methylfolate 800 µg daily for four weeks.
J Sleep Res
January 2025
Sleep and Chronobiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA.
Delayed sleep-wake phase disorder involves chronic difficulty going to bed and waking up at conventional times and often co-occurs with depression. This study compared sleep and circadian rhythms between patients with delayed sleep-wake phase disorder with depression (DSWPD-D) and without (DSWPD-ND) comorbid depression. Clinical records of 162 patients with delayed sleep-wake phase disorder (70 DSWPD-D, 92 DSWPD-ND) were analysed, including a subset of 76 patients with circadian phase determined by the dim light melatonin onset.
View Article and Find Full Text PDFAm J Sports Med
January 2025
Oregon Shoulder Institute, Medford, Oregon, USA.
Background: Despite the effectiveness of remplissage in reducing instability recurrence, debate remains about the loss of external rotation (ER) after this procedure.
Purpose: To compare the loss of ER after primary isolated arthroscopic Bankart repair alone (BR), Bankart with remplissage (REMP), and Latarjet (LAT) procedures.
Study Design: Meta-analysis; Level of evidence, 3.
Objectives: To compare lag-screw slide and revision surgery rate between two generations of the Stryker Gamma cephalomedullary nail (Stryker, Kalamazoo, MI).
Methods: Design: Retrospective chart review.
Setting: Single academic, Level-1 Trauma Center.
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