A commercial sandwich elisa (Platelia Aspergillus EIA; Bio-Rad) developed for the detection of galactomannan, a major cell wall constituent of Aspergillus species, was tested for its efficacy in the diagnosis of aspergillosis in falcons. Ninety serum samples from 50 aspergillosis-positive falcons and 182 samples from 142 aspergillosis-negative falcons were tested. The sensitivity of the test was only 12 per cent and its specificity was 95 percent. The test was therefore unsatisfactory for detecting galactomannan in the serum samples and cannot be used as a screening test for aspergillosis in falcons.
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http://dx.doi.org/10.1136/vr.158.13.442 | DOI Listing |
Aspergillosis is the most important disease in hunting/racing falcons in the Middle East. Based on clinical observations, the gyrfalcon () is considered to be more susceptible than other species of falcons, whereas it has been hypothesized that their hybrids might be more resistant. This retrospective study examined the endoscopic results of 3,754 captive-bred juvenile falcons of three different species and their hybrids, admitted to Dubai Falcon Hospital in their first year in the UAE over a 14-year period.
View Article and Find Full Text PDFJ Avian Med Surg
November 2022
Dubai Falcon Hospital, Zabeel, 23919, Dubai, United Arab Emirates.
Aspergillosis is a common disease in birds. Currently, avian aspergillosis is treated with voriconazole administered orally, although intramuscular (IM) administration increases bioavailability and is more effective in treating generalized aspergillosis. The objective of this study was to evaluate the safety of the intravenous formulation of voriconazole as an IM injection in the pectoral muscles of pigeons ( f.
View Article and Find Full Text PDFMed Mycol
September 2021
Biomedical Research Center (BRC), Faculty of Veterinary Science, University of Pretoria, Republic of South Africa (Naidoo).
Unlabelled: Posaconazole has been used anecdotally to treat aspergillosis in falcons resistant to voriconazole. In human medicine, it is used prophylactically in immunosuppressed human subjects with invasive pulmonary aspergillosis. So far, no studies have been performed in birds.
View Article and Find Full Text PDFMed Mycol
July 2020
Biomedical Research Center (BRC), Faculty of Veterinary Science, University of Pretoriaz, Republic of South Africa (Naidoo).
Voriconazole is one of the main azoles used to treat invasive aspergillosis in falconry raptors and birds. Despite the fact that there are studies for oral and intravenous use of voriconazole in birds, there are none for its effect after intramuscular use. Empirical use of intramuscular voriconazole in falcons, indicated quicker therapy response than the oral one.
View Article and Find Full Text PDFVet Clin Pathol
September 2018
Dubai Falcon Hospital/Wadi Al Safa Wildlife Center, Dubai, United Arab Emirates.
Aspergillus fungal infections continue to be a significant cause of morbidity and mortality in birds that can, in part, be attributed to the lack of a diagnostic "gold standard" for Aspergillus infection, and which delays the diagnosis, treatment, and outcome of avian patients. At present, none of the available methods in veterinary care can detect aspergillosis early enough and with the accuracy, precision, and specificity required of an ideal diagnostic tool. Therefore, researching methods of Aspergillus detection is still an active area of inquiry, and novel techniques continue to emerge.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!