AI Article Synopsis
- Many radiosensitizers are currently being used in clinical settings, and numerous new targeted therapies that may enhance radiation therapy are under development.
- The effectiveness of these new therapies, when combined with current radiation sensitizers, needs more research to understand their short-term and long-term effects.
- Free radical scavengers have potential as radioprotectors, but evidence supporting mucoprotection is not as strong.
Article Abstract
Many radiosensitizers are in current clinical use. In addition, a myriad of potential new targeted therapies, which may also interact with radiation, are in clinical development. The clinical utility of new targeted therapies, in combination with existing radiation sensitizers (chemotherapies) requires further evaluation, as does the understanding of their acute and late radiation effects. Free radical scavengers appear to show promise as radioprotectors, but data for mucoprotection are less convincing.
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| http://dx.doi.org/10.1016/j.hoc.2006.01.012 | DOI Listing |
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