Milk contains more than 40 proteins and all of them may act like human species antigens. The main allergens are beta lactoglobulin, casein, alpha lactoalbumin and seroalbumin; beta lactoglobulin is a protein not existing in human species and is found in maternal milk in minimal quantities (mcg) due to milky products ingested by the mother, these small quantities are responsible of the highest number of sensitizations to this protein. This article reviews the allergy to the cow-milk's protein, also, a critical route to its diagnosis and management is planted.
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