Hb J- Meerut [alpha 120 (H3) Ala ->Glu (alpha1)] in a Turkish male.

Int J Med Sci

Division of Hematology, Department of Internal Medicine, Istanbul Medical School, University of Istanbul, Capa, Istanbul, Turkey.

Published: April 2006

Hb J Meerut is an infrequently found alpha-globin variant. It has previously been reported in various populations around the world. One particular case reported in 1994 included a Turkish family. In this report, details of a second case of Hb J Meerut in a Turkish male who is unrelated to the first family are described. In the present case a slight increase in the oxygen affinity of Hb J Meerut, relative to that of the normal control, has been observed as detected by low p50 values in arterial whole blood. Additionally, a slight increase in red blood cell count, as compared against a normal individual, was observed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1415838PMC
http://dx.doi.org/10.7150/ijms.3.26DOI Listing

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