Background: Psoriatic onycho-pachydermo-periostitis (POPP) is a rare manifestation of psoriatic arthritis that is often misdiagnosed as a nail infection. The treatment for POPP has not yet been established.
Case Report: We present a case of a 67-year-old man who had no psoriatic skin lesions with POPP, characterized by psoriatic nail changes, painful swelling of the distal soft tissues on the great toes and fingers, and enthesopathies of the involved terminal phalanges. The clinical nail and arthritic changes were improved with methotrexate treatment 4 mg weekly for 6 months.
Conclusions: Methotrexate can be recommended as the first-choice therapeutic agent for patients with POPP.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Psoriatic Onycho-Pachydermo-Periostitis.
J Psoriasis Psoriatic Arthritis
April 2022
Department of Radiology, Imperial College Healthcare NHS Trust, London, UK.
Psoriatic onycho-pachydermo-periostitis (POPP) is an unfamiliar and poorly recognised condition first described in 1989 by Fournie et al. It is a variant of psoriatic arthritis comprising the triad of onycholysis, soft tissue thickening and radiographically apparent periostitis. Whilst typically affecting the great toe, any of the digits of the hands and feet may be affected.
View Article and Find Full Text PDFPsoriatic onycho-pachydermo periostitis (POPP): a case report treated successfully with IL-17 blockade and a literature review on characteristics, pathogenesis, and treatment.
Clin Rheumatol
November 2021
Department of Rheumatology, 424 General Army Hospital, Ring Road N. Efkarpias, 564 03, Thessaloniki, Greece.
Psoriatic onycho-pachydermo periostitis (POPP) is characterized by psoriatic onychodystrophy, connective tissue thickening, and periostitis of the distal phalanges (DPs), producing a drumstick-like deformity. Our aim was to present the first case of POPP treated successfully with an IL-17 inhibitor, perform a literature review of its characteristics and treatment, and explore the possible pathogenesis. We conducted a systematic review of previously presented POPP cases.
View Article and Find Full Text PDFRecalcitrant psoriatic onycho-pachydermo-periostitis successfully treated with guselkumab.
Clin Exp Dermatol
June 2021
Departments of, Department of, Dermatology, Galliera Hospital, Genoa, Italy.
Psoriatic onycho-pachydermo-periostitis: a patient's perspective.
Clin Exp Dermatol
January 2021
Department of Dermatology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, West Midlands, UK.
Rapid response to clinical symptoms in early psoriatic onycho-pachydermo-periostitis treated with infliximab.
Australas J Dermatol
February 2018
Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!