Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00000542-200604000-00039 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Comparison of Intrathecal Dexmedetomidine and Fentanyl as Adjuvants to 0.5% Hyperbaric Levobupivacaine for Lower Abdominal Surgeries: A Prospective, Double-Blinded, Randomized Controlled Trial.
Cureus
December 2024
Department of Anaesthesiology and Critical Care, Pacific Medical College and Hospital, Udaipur, IND.
Background Due to its affordability and ease of application, the subarachnoid block is the most frequently used method for lower abdominal procedures. Levobupivacaine has an onset of sensory and motor blockade comparable to that of bupivacaine and prolongs the duration of analgesia while facilitating quick recovery from motor block. Fentanyl and dexmedetomidine, when used as additives to intrathecal local anesthetic, can extend the duration of sensory and motor blockade and enhance postoperative analgesia.
View Article and Find Full Text PDFEnhanced Recovery After Surgery (ERAS) cardiac turnkey order set for perioperative pain management in cardiac surgery: Proceedings from the American Association for Thoracic Surgery (AATS) ERAS Conclave 2023.
JTCVS Open
December 2024
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, Md.
Objective: Optimal perioperative pain management is an essential component of perioperative care for the cardiac surgical patient. This turnkey order set is part of a series created by the Enhanced Recovery After Surgery Cardiac Society, first presented at the Annual Meeting of The American Association for Thoracic Surgery in 2023. Several guidelines and expert consensus documents have been published to provide guidance on pain management and opioid reduction in cardiac surgery.
View Article and Find Full Text PDFThe effect of dexmedetomidine vs. atracurium on intubation condition in children - a randomized clinical trial.
BMC Res Notes
January 2025
Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: Using neuromuscular blocking agents (NMBA) in pediatric induction protocol is a challenging matter. Therefore, in this study, we aimed to find a safer way for anesthesia in children. We compared the effects of dexmedetomidine with atracurium on intubation conditions in children aged 6-12 years under general anesthesia.
View Article and Find Full Text PDFDexmedetomidine in colon cancer surgery: Evaluating its impact and efficacy.
World J Gastrointest Surg
December 2024
Department of Anaesthesiology, All India Institute of Medical Sciences, Bathinda 151001, India.
We present an editorial on an article that highlights the benefits of dexmedetomidine (Dex) in colon cancer surgeries, which have been thoroughly investigated in the referenced publication involving 117 subjects. Of these patients, 59 (group A) received Dex before anesthesia induction, while 58 (group B) received normal saline. Group A patients demonstrated several advantages over Group B, including lower propofol and remifentanil requirements, improved cerebral oxygenation as measured by regional cerebral oxygen saturation, better hemodynamic stability, and reduced incidence of postoperative cognitive dysfunction.
View Article and Find Full Text PDFDexmedetomidine suppresses glucose-stimulated insulin secretion in pancreatic β-cells.
FEBS Open Bio
December 2024
Department of Cell Physiology, Institute of Biomedical Science, Kansai Medical University, Hirakata, Osaka, Japan.
Article Synopsis
- Proper glycemic control is important in critical care settings, as it can impact patient outcomes and is influenced by factors such as insulin secretion and glucose metabolism.
- Various perioperative drugs, particularly dexmedetomidine (DEX), are shown to suppress glucose-stimulated insulin secretion, but the mechanisms remain unclear.
- Research using pancreatic cell lines and primary cells indicates that DEX reduces insulin secretion without significantly altering other cellular processes, suggesting that it affects insulin signaling pathways and exocytosis mechanisms.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!