The aim of the present study was to investigate the ability of individuals with autism to represent goal-directed behavioural actions. We compared the performance of subjects with autism (n=16), mentally retarded subjects (n=14) and normal healthy subjects (n=15) in a sequencing task consisted in arranging pictures of single events in their appropriate order so as to make coherent stories. Three types of actions were presented: (a) actions on objects; (b) actions on objects in a broader spatio-temporal context; (c) interactive actions. Autistic subjects were impaired in arranging sequences of actions on objects, as compared to both control groups. This impairment might contribute to explaining both executive deficits and difficulties in understanding others' behaviour in autism.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s10803-006-0092-3 | DOI Listing |
Dokl Biochem Biophys
January 2025
Center for Strategic Planning and Management of Biomedical Health Risks, Federal Medical and Biological Agency, Moscow, Russia.
Unlabelled: The association of the pathogenesis of neurodegenerative diseases, depression, anxiety, and cognitive disorders with neurotrophin-3 deficiency determines the prospect of creating drugs with a similar mechanism of action. Since the use of full-length NT-3 is limited by unsatisfactory pharmacokinetic properties, the creation of low-molecular mimetics of neurotrophin-3 that are active when administered systemically is relevant. The Federal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies has created a dimeric dipeptide mimetic of the 4th loop of NT-3, hexamethylenediamide bis-(N-γ-oxybutyryl-L-glutamyl-L-asparagine) with the laboratory code GTS-302, which activates TrkC and TrkB receptors.
View Article and Find Full Text PDFCurr Biol
January 2025
Department of Psychology, University of Virginia, Charlottesville, VA 22904, USA; Department of Biology, University of Virginia, Charlottesville, VA 22904, USA. Electronic address:
Visual motion is a crucial cue for the brain to track objects and take appropriate actions, enabling effective interactions with the environment. Here, we study how the superior colliculus (SC) integrates motion information using asymmetric plaids composed of drifting gratings of different directions and speeds. With both in vivo electrophysiology and two-photon calcium imaging, we find that mouse SC neurons integrate motion direction by performing vector summation of the component gratings.
View Article and Find Full Text PDFJ Speech Lang Hear Res
January 2025
Department of Speech, Language, and Hearing Sciences, The University of Arizona, Tucson.
Purpose: The purpose of this study was to determine if the Vocabulary Acquisition and Usage for Late Talkers (VAULT) intervention could be efficaciously applied to a new treatment target: words a child neither understood nor said. We also assessed whether the type of context variability used to encourage semantic learning (i.e.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
School of Physics, Beihang University, Beijing 100191, China.
Exploiting biomimetic perception of invisible spectra in flexible artificial human vision systems (HVSs) is crucial for real-time dynamic information processing. Nevertheless, the fast processing of motion objects in natural environments poses a challenge, necessitating that these artificial HVSs simultaneously have swift photoresponse and nonvolatile memory. Here, inspired by the human retina, we propose a flexible UV neuromorphic visual synaptic device (NeuVSD) based on GaO@GaN-composited nanowires for dynamic visual perception.
View Article and Find Full Text PDFInfancy
January 2025
Donders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands.
The ability to recognize and act on others' emotions is crucial for navigating social interactions successfully and learning about the world. One way in which others' emotions are observable is through their movement kinematics. Movement information is available even at a distance or when an individual's face is not visible.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!