Objective: The effectiveness of the left ventricle (LV) geometry reconstruction (Dor procedure) as the method of surgical treatment of LV post-infarction aneurysm and large dilated myocardial scars is well established. The efficacy of LV restoration in cases of globally dilated hypofunctional LV, containing the same spherical architecture as scarred, remains questionable.
Methods: The results of LV geometry reconstruction in small population of patients with ischemic dilated cardiomyopathy (IDCMP) and predominantly hypokinetic LV are described in 14 patients of that underwent LV rebuilding into a conical architecture. Surgical procedures included LV geometry reconstruction with the synthetic patch, narrowing of widened dimensions between papillary muscles, coronary artery bypass grafting (CABG) and, in several cases, mitral and tricuspid valves annuloplasty.
Results: Initial mean end-diastolic and end-systolic volumes indexes were 177 and 112 ml/m2, respectively, mean LV ejection fraction (EF) of 32.9%. The analysis of immediate and mid-term (1 and 4 years) results proved that LV reconstruction markedly decreased LV volumes and increased LVEF an average of +12% above resting values with significant improvement in clinical status.
Conclusions: A rebuilding procedure for the scarred heart is now introduced to be used in ischemic patients with dilated ischemic cardiomyopathy without significant scar. Preliminary structural and physiological results imply that creating an elliptical form has potential importance during LV reconstruction of very sick patients with IDCMP without discrete scar.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ejcts.2006.02.057 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
In the realm of 3D measurement, photometric stereo excels in capturing high-frequency details but suffers from accumulated errors that lead to low-frequency distortions in the reconstructed surface. Conversely, light field (LF) reconstruction provides satisfactory low-frequency geometry but sacrifices spatial resolution, impacting high-frequency detail quality. To tackle these challenges, we propose a photometric stereoscopic light field measurement (PSLFM) scheme that harnesses the strengths of both methods.
View Article and Find Full Text PDFDue to their advantages of compact geometries and lightweight, diffractive optical elements (DOEs) are attractive in various applications such as sensing, imaging and holographic display. When designing DOEs based on algorithms, a diffraction model is required to trace the diffracted light propagation and to predict the performance. To have more precise diffraction field tracing and optical performance simulation, different diffraction models have been proposed and developed.
View Article and Find Full Text PDFExploring the feasibility of millimeter-wave sensors for non-invasive respiratory motion visualization in diagnostic imaging and therapy.
Med Phys
January 2025
Department of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osakasayama, Osaka, Japan.
Background: Management of respiratory motion during radiation therapy is essential for accurate dose delivery and minimizing the risk to organs. In diagnostic imaging, respiratory monitoring is required for confirmation of breath-hold and four-dimensional computed tomography (CT) reconstruction. Although respiratory monitoring systems are widely used in radiation therapy, they are not often used for diagnostic imaging, where they could improve image quality.
View Article and Find Full Text PDFAmplification of Secondary Flow at the Initiation Site of Intracranial Sidewall Aneurysms.
Cardiovasc Eng Technol
January 2025
Department of Hydrodynamic Systems, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Műegyetem rkp. 1-3, Budapest, 1111, Hungary.
Purpose: The initiation of intracranial aneurysms has long been studied, mainly by the evaluation of the wall shear stress field. However, the debate about the emergence of hemodynamic stimuli still persists. This paper builds on our previous hypothesis that secondary flows play an important role in the formation cascade by examining the relationship between flow physics and vessel geometry.
View Article and Find Full Text PDFPredicting inflammatory response of biomimetic nanofibre scaffolds for tissue regeneration using machine learning and graph theory.
J Mater Chem B
January 2025
Biomaterials Drug Delivery and Nanotechnology Unit, Centre for Biomedical and Biomaterials Research (CBBR), University of Mauritius, Réduit, Mauritius.
Tissue regeneration after a wound occurs through three main overlapping and interrelated stages namely inflammatory, proliferative, and remodelling phases, respectively. The inflammatory phase is key for successful tissue reconstruction and triggers the proliferative phase. The macrophages in the non-healing wounds remain in the inflammatory loop, but their phenotypes can be changed interactions with nanofibre-based scaffolds mimicking the organisation of the native structural support of healthy tissues.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!