AI Article Synopsis
- Congenital heart disease (CHD) refers to structural defects in the heart or large blood vessels that are present at birth, resulting from disruptions during fetal heart development.
- These defects may arise spontaneously or as a result of exposure to drugs or toxins, and while congenital doesn’t mean inherited, some defects can be passed down through genetics.
- Diagnosing CHD is crucial for the individual’s health and helps to prevent the continuation of these defects in future generations through selective breeding.
Article Abstract
Congenital heart disease (CHD) is defined as a morphologic defect of the heart or associated great vessels present at birth. Abnormalities are caused by alterations or arrests in particular phases of embryonic development of the fetal heart. The term congenital does not imply that the defect was inherited, and the defect may have occurred spontaneously or secondary to a drug or toxin. By studying families of animals with specific CHDs, many defects have also been shown to be heritable.Additionally, if the defect was caused by a spontaneous de novo mutation,that individual has the potential to transmit the mutation to offspring. The diagnosis of CHD is important not only to the health of the patient but to eliminate affected individuals from the breeding pool.
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| http://dx.doi.org/10.1016/j.cvsm.2005.12.006 | DOI Listing |
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