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[Clinical analysis of histocytic necrotizing lymphadenitis]. | LitMetric

[Clinical analysis of histocytic necrotizing lymphadenitis].

Zhong Nan Da Xue Xue Bao Yi Xue Ban

Department of Hematology,Second Xiangya Hospital, Central South University, Changsha 410011, China.

Published: February 2006

AI Article Synopsis

Article Abstract

Objective: To understand the clinical features and histopathology of histocytic necrotizing lymphadenitis (HNL) so as to better recognize the disease.

Methods: The clinical features, histopathology, and diagnosis of 10 patients admitted to our hospital were retrospectively analyzed.

Results: The clinical features of these 10 cases included: young females were the majority; lymphadenopathy and fever were the most common clinical manifestations; some cases were accompanied by connective tissue diseases. Histopathologic examination showed distinctive necrosis and around the necrotic foci, variable proliferations of histocytes but generally without infiltration of neutrophils.

Conclusion: HNL has some typical histopathological alterations and relatively fine prognosis,but it tends to be misdiagnosed as lymphoma or lymphoid tuberculosis and may be accompanied by other diseases.

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