Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC374787 | PMC |
| http://dx.doi.org/10.1128/jb.42.5.689-693.1941 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of a dry powder formulation for pulmonary delivery of azithromycin-loaded nanoparticles.
J Pharm Pharm Sci
October 2024
Department of Biochemical and Pharmaceutical Technology, University of São Paulo, São Paulo, Brazil.
Article Synopsis
- The study focuses on developing a non-invasive inhalation method using polycaprolactone nanoparticles to deliver azithromycin for treating respiratory diseases like COVID-19 and pneumonia.
- The nanoparticles were created via an emulsion technique, producing a fine powder formulation that shows high encapsulation efficiency and favorable size for pulmonary delivery.
- Testing revealed the formulation maintains azithromycin’s antimicrobial effectiveness without causing cytotoxicity to human lung cells, indicating potential for improved treatment of lung infections.
The desire of autonomy: A lever for vaccination of the elderly? Results of a qualitative study.
Hum Vaccin Immunother
December 2024
Centre International de Recherche en Infectiologie, Team GIMAP, Université Jean Monnet, Université Claude Bernard, Lyon, France.
Article Synopsis
- The COVID-19 pandemic has exposed low vaccination rates among the elderly in France and identified barriers to their immunization.
- A qualitative study involving semi-structured interviews with seniors revealed that while they prioritize health through exercise and diet, they do not view vaccination as crucial for preventing infections.
- Finding that seniors often overlook the link between vaccination and maintaining autonomy, the study suggests using the health benefits of vaccines to encourage greater uptake among this population.
Glutamine enhances pneumococcal growth under methionine semi-starvation by elevating intracellular pH.
Front Microbiol
July 2024
Department of Basic Medical Science, School of Medicine, Lishui University, Lishui, Zhejiang, China.
Introduction: Bacteria frequently encounter nutrient limitation in nature. The ability of living in this nutrient shortage environment is vital for bacteria to preserve their population and important for some pathogenic bacteria to cause infectious diseases. Usually, we study how bacteria survive after nutrient depletion, a total starvation condition when bacteria almost cease growth and try to survive.
View Article and Find Full Text PDFLiposome-based dry powder vaccine immunization targeting the lungs induces broad protection against pneumococcus.
J Control Release
April 2024
Laboratório de Bacteriologia, Instituto Butantan, São Paulo, Brazil; Programa de Pós-Graduação Interunidades em Biotecnologia, Universidade de São Paulo, São Paulo, Brazil. Electronic address:
Streptococcus pneumoniae is an important human pathogen. Currently used conjugate vaccines are effective against invasive disease, but protection is restricted to serotypes included in the formulation, leading to serotype replacement. Furthermore, protection against non-invasive disease is reported to be considerably lower.
View Article and Find Full Text PDFSerial Evaluation of Preimmunization Antibody Titers in Lymphoma Patients Receiving Chimeric Antigen Receptor T Cell Therapy.
Transplant Cell Ther
April 2024
Division of Hematology, Mayo Clinic, Rochester, Minnesota. Electronic address:
Antibody titers and the potential need for immunization have not been formally studied in recipients of chimeric antigen receptor T cell therapy (CAR-T). Prior studies have shown that CD19-targeted CAR-T can induce persistent B cell aplasia but preserve plasma cells for humoral response. Aiming to assess the immune repertoire and antibody titer status of CAR-T recipients, we conducted a retrospective study of immune cell recovery and antibody titers to vaccines in anti-CD19 CAR-T recipients at Mayo Clinic, Rochester.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!