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Predicting Survival Rates in Brain Metastases Patients from Non-Small Cell Lung Cancer Using Radiomic Signatures Associated with Tumor Immune Heterogeneity.
Adv Sci (Weinh)
January 2025
The department of oncology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Non-small cell lung cancer (NSCLC) frequently metastasizes to the brain, significantly worsened prognoses. This study aimed to develop an interpretable model for predicting survival in NSCLC patients with brain metastases (BM) integrating radiomic features and RNA sequencing data. 292 samples are collected and analyzed utilizing T1/T2 MRIs.
View Article and Find Full Text PDFSevere Ethylene Glycol Toxicity: Multidisciplinary Management and Long-Term Renal Implications.
Cureus
December 2024
Internal Medicine, Griffin Hospital, Derby, USA.
Ethylene glycol (C₂H₆O₂), a toxic alcohol commonly found in automotive antifreeze, de-icing solutions, and industrial coolants, can cause severe toxicity when ingested. Due to its sweet taste, it is often consumed accidentally or intentionally, leading to life-threatening consequences such as metabolic acidosis, acute kidney injury (AKI), and mortality. Prompt diagnosis and early treatment with antidotes such as fomepizole or ethanol, combined with hemodialysis, are essential in preventing severe outcomes.
View Article and Find Full Text PDFBibliometric Insights Into Thromboelastography Research Using PubMed and VOSviewer.
Cureus
December 2024
Department of Anesthesiology, Tata Main Hospital, Jamshedpur, IND.
Thromboelastography (TEG) has evolved from a primarily surgical tool to a key instrument in broader medical fields, including personalized medicine for coagulopathies. The rationale for conducting this bibliometric analysis of TEG is to understand the evolution and current state of research in this critical field. By identifying publication trends, key contributors, and major developments, this study aims to provide valuable insights to guide future research and clinical practices in TEG.
View Article and Find Full Text PDFBridging brain and blood: a prospective view on neuroimaging-exosome correlations in HIV-associated neurocognitive disorders.
Front Neurol
January 2025
Department of Radiology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
HIV-associated neurocognitive disorder (HAND) is a complex neurological complication resulting from human immunodeficiency virus (HIV) infection, affecting about 50% of individuals with HIV and significantly diminishing their quality of life. HAND includes a variety of cognitive, motor, and behavioral disorders, severely impacting patients' quality of life and social functioning. Although combination antiretroviral therapy (cART) has greatly improved the prognosis for HIV patients, the incidence of HAND remains high, underscoring the urgent need to better understand its pathological mechanisms and develop early diagnostic methods.
View Article and Find Full Text PDFReducing Employee Injuries from Aggressive Patient Behavior at Children's Hospital by Implementing a Behavioral Response Team.
Pediatr Qual Saf
January 2025
Department of Pediatrics and Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Background: Among hospitalized children, episodes of aggressive patient behavior place healthcare staff at risk for serious injuries. By implementing a behavioral response team at a children's hospital, we aimed to reduce monthly employee injuries related to aggressive patient behavior from 3.4 to 2.
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