Objective: To determine if differences exist in prescribing for cerebrovascular adverse event (CAE) prophylaxis between residents receiving risperidone therapy and those with no antipsychotic therapy.
Design: Retrospective, multicentered, cross-sectional study.
Setting: Ten long-term care facilities.
Participants: A total of 200 residents residing in skilled nursing facilities. The study group (n = 95) included residents with a risk factor for a CAE receiving risperidone. The control group (n = 105) consisted of residents with a risk factor for a CAE and not receiving antipsychotic therapy.
Measurements: Data collected included patient age, gender, risk factor for CAE, and CAE prophylaxis. Statistics were performed using Chi-squared tests.
Results: Fifty-six percent of the study group was not on an agent for CAE prophylaxis, compared with 36% of the control group.
Conclusion: This study demonstrated with statistical significance that CAE prophylaxis was less likely in the risperidone group. We are implementing a pharmacist-driven initiative to add antiplatelet therapies in all patients who have at least one risk factor for CAE.
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http://dx.doi.org/10.4140/tcp.n.2005.747 | DOI Listing |
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January 2025
Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, 130122, People's Republic of China.
Monkeypox virus (MPXV) is an important zoonotic pathogenic virus, which poses serious threats to public health. MPXV infection can be prevented by immunization against the variola virus. Because of the safety risks and side effects of vaccination with live vaccinia virus (VACV) strain Tian Tan (VTT), we constructed two gene-deleted VTT recombinants (TTVAC7 and TTVC5).
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January 2025
State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Medical University, Urumqi, 830000, China.
Alveolar echinococcosis (AE) is an infrequent zoonosis caused by Echinococcus multilocularis with a high degree of disability and mortality. Metastatic cerebral alveolar echinococcosis (CAE) is very rare and the lesions could lead to severe perilesional brain edema (PLBE) and subsequent uncontrollable intracranial hypertension. In this study, we sought to determine the expression of edema-associated factors in CAE lesions and their associations with PLBE.
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Department of Functional Biology, University of Oviedo, Oviedo, Spain.
The aim of this cluster-randomised controlled trial was to investigate the training and detraining effects of two different-volume Copenhagen Adduction Exercise (CAE) protocols on adductor squeeze strength. Thirty high-level rink hockey players (14 y.o.
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Department of Engineering Mechanics, Dalian University of Technology, Dalian, China.
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Faculty of Health, Education and Life Sciences, Birmingham City University, Birmingham, UK.
Introduction: Falls are a global public health problem and the second leading cause of death from unintentional injury. Globally, approximately 30%-50% of people living in nursing or residential care homes fall each year. Falls have an impact on quality of life and morbidity.
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