The work is supposed to estimate intoxication by summary indices of the medium and low mass molecules and oligopeptides in plasma, erythrocytes and urine. The indices developed made it possible to determine the stage of endogenous intoxication and to choose differentially the optimal methods of efferent therapy or a combination of methods.
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Mapping Activity and Functional Organisation of the Motor and Visual Pathways Using ADC-fMRI in the Human Brain.
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Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
In contrast to blood-oxygenation level-dependent (BOLD) functional MRI (fMRI), which relies on changes in blood flow and oxygenation levels to infer brain activity, diffusion fMRI (DfMRI) investigates brain dynamics by monitoring alterations in the apparent diffusion coefficient (ADC) of water. These ADC changes may arise from fluctuations in neuronal morphology, providing a distinctive perspective on neural activity. The potential of ADC as an fMRI contrast (ADC-fMRI) lies in its capacity to reveal neural activity independently of neurovascular coupling, thus yielding complementary insights into brain function.
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Clin Neurol Neurosurg
January 2025
Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium; Department of Neurosciences, Catholic University Leuven, Leuven, Belgium. Electronic address:
Objective: Surgeons routinely check the pupils to assess, in part, the brain stem function and the neural integrity of the visual system. Where a relative afferent pupillary defect is difficult to notice during surgery, an efferent pupillary defect or mydriasis is clearly recognizable. Visual loss in orbital surgery is attributed to compromised perfusion of the optic nerve, retina, or choroid, but an association with mydriasis is generally not assumed.
View Article and Find Full Text PDFMultidimensional free shape-morphing flexible neuromorphic devices with regulation at arbitrary points.
Nat Commun
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View Article and Find Full Text PDFEffect of Medial Olivocochlear Efferents on Speech Discrimination in Noise in Multiple Sclerosis.
Noise Health
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Am J Physiol Endocrinol Metab
January 2025
Autonomic Physiology Laboratory, Faculty of Life Science and Human Technology, Nara Women's University, Kita-Uoya Nishimachi, Nara, 630-8506, Japan.
The current study aimed to propose a method to directly measure right cervical vagal nerve activity (cVNA) alongside renal sympathetic nerve activity (RSNA) in conscious rats. The right cervical vagus nerve was surgically exposed and fitted with a bipolar electrode to record cVNA. A microcatheter was used to administer levobupivacaine to selectively block afferent cVNA.
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