Some protease inhibitors use uncommon mechanisms to restrain the activity of their target enzymes. A recent paper in Chemistry and Biology (Lu et al., 2006) demonstrates a curious mechanism of inhibition of a caspase, relying on principles of native peptide ligation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.molcel.2006.03.001 | DOI Listing |
Publication Analysis
Top Keywords
chemical ligation--an
4
ligation--an unusual
4
unusual paradigm
4
paradigm protease
4
protease inhibition
4
inhibition protease
4
protease inhibitors
4
inhibitors uncommon
4
uncommon mechanisms
4
mechanisms restrain
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!