2-Aryl-6-cyano-7-methyl-5-indolizinones were successfully converted into 2-aryl-5-chloro-6-cyano-7-methylindolizines. The obtained 5-chloroindolizines readily underwent nucleophilic substitution at position 5 leading in high yields to novel 5-functionalised indolizines.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399457 | PMC |
| http://dx.doi.org/10.1186/1860-5397-1-9 | DOI Listing |
Publication Analysis
Top Keywords
nucleophilic substitution
8
efficient synthesis
4
synthesis 5-substituted
4
5-substituted 2-aryl-6-cyanoindolizines
4
2-aryl-6-cyanoindolizines nucleophilic
4
substitution reactions
4
reactions 2-aryl-6-cyano-7-methyl-5-indolizinones
4
2-aryl-6-cyano-7-methyl-5-indolizinones converted
4
converted 2-aryl-5-chloro-6-cyano-7-methylindolizines
4
2-aryl-5-chloro-6-cyano-7-methylindolizines 5-chloroindolizines
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!