[Study of toxicity of iodophor,glutaradehyde and chlorhexidine to L929 Cells.].

Shanghai Kou Qiang Yi Xue

Department of Oral Pharmacology,School of Stomatology, Shanghai Second Medical University. Shanghai 200011,China.

Published: June 1995

We comparatively studied the toxicity of iodophor,glutaradehyde and chlorhexidine in different concentration and time.The result shows that the toxicity of iodophor to L929 cells is the lowest in all kinds of drug concentration and action time is much lower than that of glutaradehyde and chlorhexidine(P<0.05) with prolonging time.It indicates that iodophor can be used to oral diseases therapy with lower concentration.

Download full-text PDF

Source

Publication Analysis

Top Keywords

toxicity iodophorglutaradehyde
8
iodophorglutaradehyde chlorhexidine
8
[study toxicity
4
chlorhexidine l929
4
l929 cells]
4
cells] comparatively
4
comparatively studied
4
studied toxicity
4
chlorhexidine concentration
4
concentration timethe
4

Similar Publications

Immune checkpoint blockade (ICB) has significantly improved the survival for many patients with advanced malignancy. However, fewer than 50% of patients benefit from ICB, highlighting the need for more effective immunotherapy options. High-dose interleukin-2 (HD IL-2) immunotherapy, which is approved for patients with metastatic melanoma and renal cell carcinoma, stimulates CD8 T cells and NK cells and can generate durable responses in a subset of patients.

View Article and Find Full Text PDF

Background: Oxidative stress is strongly linked to neurodegeneration through the activation of c-Abl kinase, which arrests α-synuclein proteolysis by interacting with parkin interacting substrate (PARIS) and aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 (AIMP2). This activation, triggered by ataxia-telangiectasia mutated (ATM) kinase, leads to dopaminergic neuron loss and α-synuclein aggregation, a critical pathophysiological aspect of Parkinson's disease (PD). To halt PD progression, pharmacological inhibition of c-Abl kinase is essential.

View Article and Find Full Text PDF

Background: We continue to struggle with the prevention and treatment of the influenza virus. The 2009 swine flu pandemic, caused by the H1N1 strain of influenza A, resulted in numerous fatalities. The threat of influenza remains a significant concern for global health, and the development of novel drugs targeting these viruses is highly desirable.

View Article and Find Full Text PDF

Introduction: This case study presents a rare and fatal instance of Toxic Epidermal Necrolysis (TEN) and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome in a 51-year-old male patient diagnosed with Rheumatoid Arthritis (RA).

Case Presentation: The patient was initially treated with sulfasalazine, leflunomide, and hydroxychloroquine, following which he developed a rash, fever, and loose stools. Drug allergy was suspected, and the antirheumatic medications were withdrawn, following which, the patient improved.

View Article and Find Full Text PDF

Titanium dioxide nanoparticles (TiONPs) as an emerging pollutant in aquatic environments can interact with metals reducing or enhancing their toxicity in these environments. This study examined and compared the toxic effects of mercury ions (Hg ions) on immobilization percentage, fatty acid profile, and oxidative stress of nauplii, individually (Hg) and simultaneously in the presence of 0.10 mg.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!