Strategies and decisions to protect emergency responders, the public, and critical infrastructure against the effects of a radiological dispersal device detonated outdoors must be made in the planning stage, not in the early period just after an attack. This contrasts with planning for small-scale types of radiological or nuclear emergencies, or for a large-scale nuclear-power-type accident that evolves over many hours or days before radioactivity is released to the environment, such that its effects can be prospectively modeled and analyzed. By the time it is known an attack has occurred, most likely there will have been casualties, all the radioactive material will have been released, plume growth will be progressing, and there will be no time left for evaluating possible countermeasures. This paper offers guidance to planners, first responders, and senior decision makers to assist them in developing strategies for protective actions and operational procedures for the first 48 hours after an explosive radiological dispersal device has been detonated.
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http://dx.doi.org/10.1097/01.HP.0000196111.16261.ed | DOI Listing |
Adv Mater
January 2025
Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou, 215123, China.
The cGAS-STING pathway is pivotal in initiating antitumor immunity. However, tumor metabolism, particularly glycolysis, negatively regulates the activation of the cGAS-STING pathway. Herein, Mn galvanic cells (MnG) are prepared via liquid-phase exfoliation and in situ galvanic replacement to modulate tumor metabolism, thereby enhancing cGAS-STING activation for bidirectional synergistic H-immunotherapy.
View Article and Find Full Text PDFBrain Commun
January 2025
Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Sodium MRI can measure sodium concentrations in people with multiple sclerosis, but the extent to which these alterations reflect metabolic dysfunction in the absence of tissue damage or neuroaxonal loss remains uncertain. Increases in total sodium concentration and extracellular sodium concentration are believed to be indicative of tissue disruption and extracellular space expansion. Conversely, increase in intracellular sodium concentration may represent early and transient responses to neuronal insult, preceding overt tissue damage.
View Article and Find Full Text PDFCureus
December 2024
Research Institute, Medical University of Pleven, Pleven, BGR.
Splenic cysts are rare medical conditions, and their incidence is dominated by parasitic types. Non-parasitic splenic cysts, whether true cysts (with a cellular lining of the cystic wall) or pseudocysts (without a cellular lining), are significantly rarer than parasitic ones. Their etiology is not fully established, with fetal remnant development, metaplasia, and mesothelial invagination being widely accepted possible mechanisms.
View Article and Find Full Text PDFSci Rep
January 2025
Physics Department, Faculty of Science, Fayoum University, Fayoum, Egypt.
For the purpose of this study, four natural rock samples-namely, diorite, granodiorite, tonalite, and granite-are being investigated about their radiation attenuation. The elemental composition of the rocks was obtained through Energy dispersive X-ray spectroscopy (EDX) which examines the microstructural and localized area elemental analyses of the four rock samples. A Monte Carlo simulation (MCNP) was used to determine and evaluate the investigated samples.
View Article and Find Full Text PDFBMC Cardiovasc Disord
January 2025
Department of Radiology, Qujing No.1 Hospital, Kirin District Garden Road no. 1, Qujing, 655099, China.
Background: Left ventricular (LV) myocardial contraction patterns can be assessed using LV mechanical dispersion (LVMD), a parameter closely associated with electrical activation patterns. Despite its potential clinical significance, limited research has been conducted on LVMD following myocardial infarction (MI). This study aims to evaluate the predictive value of cardiac magnetic resonance (CMR)-derived LVMD for adverse clinical outcomes and to explore its correlation with myocardial scar heterogeneity.
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