AI Article Synopsis
- Foods rich in resistant starch can enhance human health and reduce the risk of chronic diseases.
- RNA interference was used to reduce two types of starch-branching enzymes (SBEIIa and SBEIIb) in wheat to increase amylose levels.
- Feed trials with rats showed that wheat with over 70% amylose improved large bowel function, indicating its potential health benefits.
Article Abstract
Foods high in resistant starch have the potential to improve human health and lower the risk of serious noninfectious diseases. RNA interference was used to down-regulate the two different isoforms of starch-branching enzyme (SBE) II (SBEIIa and SBEIIb) in wheat endosperm to raise its amylose content. Suppression of SBEIIb expression alone had no effect on amylose content; however, suppression of both SBEIIa and SBEIIb expression resulted in starch containing >70% amylose. When the >70% amylose wheat grain was fed to rats in a diet as a wholemeal, several indices of large-bowel function, including short-chain fatty acids, were improved relative to standard wholemeal wheat. These results indicate that this high-amylose wheat has a significant potential to improve human health through its resistant starch content.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450120 | PMC |
| http://dx.doi.org/10.1073/pnas.0510737103 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!