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Cinnamon for Metabolic Diseases and Their Cardiovascular and Hepatic Complications: A Mechanistic Review.
Am J Chin Med
January 2025
The First Clinical College of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning 110000, P. R. China.
Cinnamon is one of the world's oldest and most popular spices, and is derived from the inner bark of several tree species from the genus Cinnamomum. During the last two decades, cinnamon has demonstrated beneficial metabolic effects not only in animal experiments but also in clinical trials. Even recent meta-analyses have shown the protective effects of cinnamon on different components of metabolic syndrome and their complications.
View Article and Find Full Text PDFBackgrounds And Aims: Daily lifestyle plays a vital role in modifying the risk for cardiovascular diseases (CVDs). Our daily life isn't inseparable from nutrition intake. As such, tea and coffee are often regarded as the most consumed beverages worldwide.
View Article and Find Full Text PDFCardioprotective potential of oleuropein, hydroxytyrosol, oleocanthal and their combination: Unravelling complementary effects on acute myocardial infarction and metabolic syndrome.
Redox Biol
October 2024
Laboratory of Pharmacology, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupolis, Zografou, Athens, Greece. Electronic address:
Clinical studies have previously established the role of olive products in cardiovascular disease (CVD) prevention, whilst the identification of the responsible constituents for the beneficial effects is still pending. We sought to assess and compare the cardioprotective potential of oleuropein (OL), hydroxytyrosol (HT), oleocanthal (OC) and oleanolic Acid (OA), regarding Ischemia/Reperfusion Injury (IRI) and CVD risk factors alleviation. The scope of the study was to design a potent and safe combinatorial therapy for high-cardiovascular-risk patients on a bench-to-bedside approach.
View Article and Find Full Text PDFMarine Polyphenols in Cardiovascular Health: Unraveling Structure-Activity Relationships, Mechanisms, and Therapeutic Implications.
Int J Mol Sci
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Department of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Cardiovascular diseases (CVDs) are responsible for significant mortality rates globally that have been raised due to the limitation of the available treatments and prevalence of CVDs. The innovative research and identification of potential preventives for CVDs are essential to alleviate global deaths and complications. The marine environment is a rich source of bioactive substances and provides a unique chemical arsenal against numerous ailments due to its unrivaled biodiversity.
View Article and Find Full Text PDFUnraveling the role of cytochrome P450 enzymes in oleanane triterpenoid biosynthesis in arjuna tree.
Plant J
September 2024
Plant Biotechnology Division, Council of Scientific and Industrial Research-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, 226015, India.
Article Synopsis
- Researchers identified specific enzymes known as cytochrome P450s that are responsible for oxidative modifications of these compounds, revealing their roles in the biosynthetic pathway of triterpenoids.
- The study concluded that the initial oxidation step in this pathway likely involves C-28 modification, with subsequent branching into different hydroxylation processes to create various beneficial compounds.
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