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http://dx.doi.org/10.1016/j.thromres.2006.01.018 | DOI Listing |
Real-world data on the uptake, effectiveness and safety of new diagnostics and disease-modifying (DMT) treatments for Alzheimer's Disease (AD) are imperative. This can be achieved through patient registries. A major challenge is how to embed registry data capture into routine clinical practice.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Toronto, Toronto, ON, Canada.
Background: Driving cessation among people with cognitive impairments (e.g., Mild Cognitive Impairment; MCI) significantly impacts their independence and overall well-being.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
The Pennsylvania State University, University Park, PA, USA.
Background: Loneliness is linked with risk for cognitive decline and dementia among older adults, but the degree to which it predicts future risk is unclear. To investigate if loneliness acts as a predictor of cognitive decline, this study employed a measurement burst design using data from the Einstein Aging Study, where loneliness and cognition were repeatedly assessed daily, for several days, across several years. In this type of data, a major challenge to detecting subtle cognitive changes is the presence of retest/practice effects.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Minnesota Duluth, Duluth, MN, USA.
Background: The rising demand for alternative dementia assessments, fueled by healthcare workforce shortages and the growing population of individuals affected with dementia, necessitates innovative approaches to address accessibility, logistics, and diverse populations. The utilization of robots in cognitive assessments emerges as a promising solution, promising efficiency and engagement, while navigating the complex landscape of dementia care challenges.
Method: Existing cognitive assessment tools were examined to develop a humanoid robot to deliver cognitive assessment.
Stroke
January 2025
Department of Neurosurgery, Oslo University Hospital-Rikshospitalet, Norway (P.K.E., A.L., P.A.R., A.G.S., L.M.V.).
Background: Subarachnoid hemorrhage (SAH) is associated with significant mortality and morbidity. The impact of SAH on human glymphatic function remains unknown.
Methods: This prospective, controlled study investigated whether human glymphatic function is altered after SAH, how it differs over time, and possible underlying mechanisms.
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