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Engineering Saccharomyces cerevisiae for medical applications.
Microb Cell Fact
January 2025
Chair of Biochemistry of Microorganisms, Faculty of Life Sciences: Food, Nutrition and Health, University of Bayreuth, 95326, Kulmbach, Germany.
Background: During the last decades, the advancements in synthetic biology opened the doors for a profusion of cost-effective, fast, and ecologically friendly medical applications priorly unimaginable. Following the trend, the genetic engineering of the baker's yeast, Saccharomyces cerevisiae, propelled its status from an instrumental ally in the food industry to a therapy and prophylaxis aid.
Main Text: In this review, we scrutinize the main applications of engineered S.
Association of Medial Temporal Lobe Cerebrovascular Reactivity and Memory Function in Older Adults With and Without Cognitive Impairment.
Neurology
January 2025
Leonard Davis School of Gerontology, University of Southern California, Los Angeles.
Background And Objectives: Cerebrovascular reactivity (CVR) represents the ability of cerebral blood vessels to regulate blood flow in response to vasoactive stimuli and is related to cognition in cerebrovascular and neurodegenerative conditions. However, few studies have examined CVR in the medial temporal lobe, known to be affected early in Alzheimer disease and to influence memory function. We aimed to examine whether medial temporal CVR is associated with memory function in older adults with and without mild cognitive impairment (MCI).
View Article and Find Full Text PDFThe many misuses of the rape kit Vintage, 2025. 256 pp.
Science
January 2025
The reviewer is the director of the Knight Science Journalism Program at the Massachusetts Institute of Technology, Cambridge, MA, USA, and the author of The Poisoner's Handbook: Murder and the Birth of Forensic Science in Jazz Age New York (Penguin, 2010).
Haphazardly applied, frequently lost, and often ignored, the vital forensic tool also has a troubling past.
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