AI Article Synopsis
- Chronic pulmonary and extrapulmonary sarcoidosis affects 10-30% of patients, presenting challenges due to its unpredictable course and the need for effective clinical evaluation methods.
- A study involving 370 patients confirmed sarcoidosis through biopsy, revealing that about 30% had a chronic form, often impacting areas like the heart and CNS.
- The study recommends implementing follow-up criteria and regular examinations to better manage and predict the disease's progression.
Article Abstract
Introduction: According to available literature data, chronic pulmonary and extrapulmonary sarcoidosis occurs in 10-30% of all sarcoidosis patients. Unpredictable course of the disease is a great challenge for scientists and researchers. Clinical and biological parameters for evaluation and prediction of the course of the disease are still the topic of different scientific investigations all over the world. According to an American case control study on sarcoidosis, unique diagnostic criteria have been established in order to simplify the diagnosis of sarcoidosis. The aim of this study was to present the morbidity and the clinical course of sarcoidosis in our patients.
Materials And Methods: We analyzed 370 sarcoidosis patients and confirmed the diagnosis of sarcoidosis by biopsy of the suspected granuloma, and by excluding any other possible cause of granulomatous inflammation. In our analyzed patients with sarcoidosis, chronic form was diagnosed in about 30%. An extremly unpredictable, chronic form of the disease was established in patients with extrapulmonary localisations (heart, CNS, liver and bones).
Conclusion: Follow-up criteria and control examinations of sarcoidosis patients are suggested as well.
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