Objectives: Although blood cultures are commonly ordered in the emergency department, there is controversy about their utility. This study aimed to determine the usefulness of blood cultures in the management of patients presenting to a tertiary adult teaching hospital emergency department in Perth, Western Australia.
Methods: A detailed chart review was undertaken of all blood cultures taken in our emergency department over a 2-month period. All patients within the hospital having blood cultures taken were identified; from this group, blood cultures originating from the emergency department were reviewed. Data were collected concerning patient demographics, culture indication, vital signs, culture outcome, disposition and alterations in management resulting from the blood culture.
Results: 218 blood cultures were ordered from the emergency department during the study period. This represented 4.0% (218/5478) of the total number of patients seen. Of the 218 cultures, only 30 were positive (13% of the study population), with 16 (7.3%) probable contaminants and 14 (6.4 %) true positives. No anaerobic isolates were identified. Of the 14 significantly positive blood cultures, the result influenced management in six patients, resulting in a useful culture rate of 2.8% (6/218).
Conclusion: Blood cultures are ordered on a significant number of patients seen in the emergency department but rarely alter management. Our findings in conjunction with other studies suggest that eliminating blood cultures in immunocompetent patients with common illnesses such as urinary tract infection, community acquired pneumonia and cellulitis, may significantly reduce the number of blood cultures, producing substantial savings without jeopardizing patient care. This needs prospective study and validation.
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http://dx.doi.org/10.1097/01.mej.0000188231.45109.ec | DOI Listing |
Infect Disord Drug Targets
January 2025
HCA Healthcare Las Palmas/Del Sol Internal Medicine Program.
Background: Streptococcal Toxic Shock Syndrome (STSS) is a life-threatening condition caused by bacterial toxins. The STSS triad encompasses high fever, hypotensive shock, and a "sunburn-like" rash with desquamation. STSS, like Toxic Shock Syndrome (TSS), is a rare complication of streptococcal infec-tions caused by Group A Streptococcus (GAS), Streptococcal pyogenes (S.
View Article and Find Full Text PDFJ Glob Infect Dis
December 2024
Department of Nephrology, Christian Medical College, Vellore, Tamil Nadu, India.
Introduction: The aim of the study was to study the clinical profile and outcomes of nocardiosis in renal allograft recipients.
Methods: This was a retrospective study of clinical outcomes in consecutive renal allograft recipients with infection over a 22-year period (2000-2022) from a tertiary care center in Southern India. The clinical data were obtained from electronic medical records and patient files.
J Glob Infect Dis
December 2024
Department of Internal Medicine, Division of Infectious Diseases, Loyola University Medical Center, Maywood, IL, USA.
Introduction: Antibiotic stewardship is a critical aspect of managing cancer patients with febrile neutropenia (FN) to limit the development of drug-resistant organisms and minimize adverse drug effects. Thus, it has been recommended that patients with FN receiving empiric antibiotics should be re-evaluated for safe antibiotic de-escalation.
Methods: Subjects treated with meropenem for febrile neutropenia who met Loyola University Medical Center's (LUMC) criteria for de-escalation were stratified based on whether meropenem was de-escalated, and 30-day all-cause mortality for both groups was assessed.
Front Cell Infect Microbiol
January 2025
Department of Clinical Laboratory, Fuding Hospital, Fujian University of Traditional Chinese Medicine, Fuding, Fujian, China.
Background: This study aimed to assess the distribution of bacteremia pathogens in elderly patients, examine the impact of gender on pathogen distribution, and evaluate the predictive value of routine blood parameters for diagnosing bacteremia.
Methods: A retrospective analysis was conducted on 151 elderly patients (≥60 years old) admitted to Fuding Hospital, Fujian University of Traditional Chinese Medicine between October 2022 and June 2023. Comprehensive routine blood tests and blood cultures were performed.
Front Cell Infect Microbiol
January 2025
Department of Clinical Laboratory, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Background: Though droplet digital PCR (ddPCR) has emerged as a promising tool for early pathogen detection in bloodstream infections (BSIs), more studies are needed to support its clinical application widely due to different ddPCR platforms with discrepant diagnostic performance. Additionally, there is still a lack of clinical data to reveal the association between pathogen loads detected by ddPCR and corresponding BSIs.
Methods: In this prospective study, 173 patients with suspected BSIs were enrolled.
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