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The Spectrum of Ocular Diseases in the Onchocerciasis-Endemic Focus of Raga in South Sudan.
Res Rep Trop Med
December 2024
Global Health Institute, University of Antwerp, Antwerp, Belgium.
Introduction: Raga County is an onchocerciasis-endemic area in the Western Bahr El Ghazal state of South Sudan, known to have a high prevalence of blindness. The objective of this study was to determine the causes of eye disease and blindness in Raga County as well as to assess the relationship of eye diseases with other prevalent conditions like onchocerciasis and epilepsy.
Methods: We reviewed unpublished pre-community directed treatment with ivermectin (CDTI) data about eye disease and onchocerciasis in Western Bahr El Ghazal including Raga.
Community-based epilepsy care in an onchocerciasis-endemic area: A 3-year cohort study in Mahenge, Tanzania.
Epilepsia
December 2024
Global Health Institute, University of Antwerp, Antwerp, Belgium.
Objective: In onchocerciasis-endemic areas, limited access to antiseizure medications (ASMs) contributes to a high epilepsy burden. This study evaluated the impact of a community-based epilepsy care program in Mahenge, Tanzania, an onchocerciasis-endemic area with high epilepsy prevalence.
Methods: A baseline survey (2017-2018) identified persons with epilepsy (PWE) in four rural villages.
Ivermectin as a promising therapeutic option for onchocerciasis-associated epilepsy.
Epilepsia Open
November 2024
Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Onchocerciasis, commonly known as river blindness, is a neglected tropical disease caused by the parasite Onchocerca volvulus. It can lead to blindness and visual impairment. Studies have also demonstrated a link between onchocerciasis and epilepsy, with there being a correlation between onchocerciasis endemicity and epilepsy prevalence.
View Article and Find Full Text PDFAttitudes and perceptions towards epilepsy in an onchocerciasis-endemic region of Tanzania: a mixed approach to determine the magnitude and driving factors.
BMC Public Health
September 2024
National Institute for Medical Research, Tanga Research Centre, Tanga, Tanzania.
Article Synopsis
- Epilepsy is a major public health issue in Tanzania, particularly in Mahenge, where stigma and misconceptions significantly impact the lives of affected individuals.
- A study involving 778 participants revealed that while most were aware of epilepsy, their knowledge was low, leading to negative attitudes and misconceptions about the disorder's causes, such as witchcraft and hereditary factors.
- Stigma towards individuals with epilepsy was prevalent, resulting in social isolation and barriers to education, with traditional healers often being the first point of treatment despite the lack of understanding of the condition.
Epidemiology of epilepsy in Wulu County, an onchocerciasis-endemic area in South Sudan.
Heliyon
September 2024
Global Health Institute, University of Antwerp, Antwerp, Belgium.
Background: We sought to investigate the epidemiology of epilepsy in Wulu County (Lakes State, South Sudan), and document the onchocerciasis transmission status in the study villages.
Methods: In February 2024, a community-based epilepsy study was conducted Wulu County and participants were surveyed via a door-to-door approach in five villages, namely: Kombi, Makundi Center, Tonjo, War-Pac, and Woko. All village residents were asked about ivermectin intake during the 2023 round of community-directed treatment with ivermectin (CDTI).
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