Bone cell proliferation on carbon nanotubes.

Nano Lett

Department of Biochemistry, University of California, Riverside, 92521, USA.

Published: March 2006

AI Article Synopsis

  • The study investigates carbon nanotubes (CNTs) as scaffolds for promoting the growth of osteoblasts and bone formation.
  • Chemical modifications were made to single-walled (SW) and multiwalled (MW) CNTs to optimize osteosarcoma ROS 17/2.8 cell culture.
  • Neutral electric charge on CNTs resulted in increased cell growth and the formation of plate-shaped crystals, while MWNTs caused significant changes in the morphology and plasma membrane functions of osteoblasts.

Article Abstract

We explored the use of carbon nanotubes (CNTs) as suitable scaffold materials for osteoblast proliferation and bone formation. With the aim of controlling cell growth, osteosarcoma ROS 17/2.8 cells were cultured on chemically modified single-walled (SW) and multiwalled (MW) CNTs. CNTs carrying neutral electric charge sustained the highest cell growth and production of plate-shaped crystals. There was a dramatic change in cell morphology in osteoblasts cultured on MWNTs, which correlated with changes in plasma membrane functions.

Download full-text PDF

Source
http://dx.doi.org/10.1021/nl051861eDOI Listing

Publication Analysis

Top Keywords

carbon nanotubes
8
cell growth
8
bone cell
4
cell proliferation
4
proliferation carbon
4
nanotubes explored
4
explored carbon
4
nanotubes cnts
4
cnts suitable
4
suitable scaffold
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!