Smoking is a very common addiction and a reason of many serious diseases of cardiovascular, respiratory and digestive systems and also a cancer. Active and passive smokers are exposed to nicotine and many carcinogenic products of tobacco smoke. Carotenoids (e.g. beta-carotene, lycopene) as natural, plant-derived antioxidants may decrease a risk of diseases connected with smoking. In accordance with literature, low level of carotenoids in blood plasma of smokers was observed and diet supplementation by carotenoids may compensate their deficit. However there are some reports in the literature that supplementation by high doses of beta-carotene may be dangerous for smokers.
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Heliyon
January 2025
Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, Makkah, 23955, Saudi Arabia.
Antarctica's harsh environmental conditions, characterized by high levels of ultraviolet (UV) radiation, pose challenges for microorganisms. To survive in these extreme cold regions with heightened UV exposure, microorganisms employ various adaptive strategies, including photoprotective carotenoid synthesis. Carotenoids are garnering attention in the skin health industry because of their UV photoprotection potential, given the direct relationship between UV exposure and skin burns, and cancer.
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January 2025
Warsaw University of Life Sciences, Institute of Food Sciences, Department of Food Technology and Assessment, Nowoursynowska St. 166, 02-787 Warsaw, Poland. Electronic address:
The study aimed to evaluate the effect of ultrasound maceration of cold-pressed oils with freeze-dried mullein flowers (Verbascum thapsus L.) on their oxidative stability and chemical composition. After the maceration process, oils' were subjected to their oxidative stability (80-120 °C) and their chemical composition, Moreover, oils kinetics parameters were calculated.
View Article and Find Full Text PDFBrief Bioinform
November 2024
Department of Biology, École Normale Supérieure, 46 rue d'Ulm, 75005 Paris, France.
Acute Promyelocytic Leukaemia (APL) arises from an aberrant chromosomal translocation involving the Retinoic Acid Receptor Alpha (RARA) gene, predominantly with the Promyelocytic Leukaemia (PML) or Promyelocytic Leukaemia Zinc Finger (PLZF) genes. The resulting oncoproteins block the haematopoietic differentiation program promoting aberrant proliferative promyelocytes. Retinoic Acid (RA) therapy is successful in most of the PML::RARA patients, while PLZF::RARA patients frequently become resistant and relapse.
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